ID A0A1H6Z2U3_9BURK Unreviewed; 481 AA.
AC A0A1H6Z2U3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=HD domain-containing protein {ECO:0000313|EMBL:SEJ43922.1};
GN ORFNames=SAMN05518853_10247 {ECO:0000313|EMBL:SEJ43922.1};
OS Variovorax sp. OK202.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=1884311 {ECO:0000313|EMBL:SEJ43922.1, ECO:0000313|Proteomes:UP000199192};
RN [1] {ECO:0000313|EMBL:SEJ43922.1, ECO:0000313|Proteomes:UP000199192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OK202 {ECO:0000313|EMBL:SEJ43922.1,
RC ECO:0000313|Proteomes:UP000199192};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FNZJ01000002; SEJ43922.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H6Z2U3; -.
DR Proteomes; UP000199192; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:UniProt.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00077; HDc; 1.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR Pfam; PF00196; GerE; 1.
DR Pfam; PF13487; HD_5; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51832; HD_GYP; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022840}.
FT DOMAIN 222..418
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
FT DOMAIN 414..479
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
SQ SEQUENCE 481 AA; 50628 MW; 3B7D93972B8CF945 CRC64;
MQPSSPIQVF DAIRALAFVG DLSMGQPIDH SARTAWLASH LAAAAGCDEA VQGHAACASL
LRWSGCTANA PEFSDLLGDD VGGRRTMLAT ASARAAADFA GSISPLAEIH CEVSGDIART
LGMPAAVELP LRHMFETFDG QGKPLGLEAA RIPLEVFIVT VAGDLEIFSR VHGLNNALRY
IAERADARYP AFLVDAAHRH AVDWLHMLEQ GASTEPMPVP TALQDITAPL ELIADVIDLK
LPWMTGYSRR VAEAAQRGAA AMGLEPAQQQ RIYRAGLIHG IGRASVPNGV WDSPGVRSEA
DAERLRLVPY WTERAARRID TLRAEAEIAS FVDERLDGSG FFRGVKGAAI DAEGRVLAAA
AHWVSLNTAR PGKPALAQAE AVAALRAEGD AGRLDAQAIA ALTGHPASAA AASPADASAL
LSGREVEVLG RISLGESNKE AARSLGISPS TVRAHLENIF RKLGCTTRAA ATLKALTLGL
L
//
