ID   A0A1H7GPY1_9FIRM        Unreviewed;       364 AA.
AC   A0A1H7GPY1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=tryptophan--tRNA ligase {ECO:0000256|ARBA:ARBA00013161};
DE            EC=6.1.1.2 {ECO:0000256|ARBA:ARBA00013161};
GN   ORFNames=SAMN04487770_101334 {ECO:0000313|EMBL:SEK40213.1};
OS   Butyrivibrio sp. ob235.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Butyrivibrio.
OX   NCBI_TaxID=1761780 {ECO:0000313|EMBL:SEK40213.1, ECO:0000313|Proteomes:UP000199418};
RN   [1] {ECO:0000313|EMBL:SEK40213.1, ECO:0000313|Proteomes:UP000199418}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OB235 {ECO:0000313|EMBL:SEK40213.1,
RC   ECO:0000313|Proteomes:UP000199418};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC       {ECO:0000256|ARBA:ARBA00005594, ECO:0000256|RuleBase:RU363036}.
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DR   EMBL; FOBE01000001; SEK40213.1; -; Genomic_DNA.
DR   RefSeq; WP_022760079.1; NZ_FOBE01000001.1.
DR   AlphaFoldDB; A0A1H7GPY1; -.
DR   OrthoDB; 9801042at2; -.
DR   Proteomes; UP000199418; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004830; F:tryptophan-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006436; P:tryptophanyl-tRNA aminoacylation; IEA:InterPro.
DR   CDD; cd00806; TrpRS_core; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   Gene3D; 1.10.240.10; Tyrosyl-Transfer RNA Synthetase; 1.
DR   InterPro; IPR001412; aa-tRNA-synth_I_CS.
DR   InterPro; IPR002305; aa-tRNA-synth_Ic.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR002306; Trp-tRNA-ligase.
DR   NCBIfam; TIGR00233; trpS; 1.
DR   PANTHER; PTHR43766; TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43766:SF1; TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL; 1.
DR   Pfam; PF00579; tRNA-synt_1b; 1.
DR   PRINTS; PR01039; TRNASYNTHTRP.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR   PROSITE; PS00178; AA_TRNA_LIGASE_I; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW   ECO:0000256|RuleBase:RU363036};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363036};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363036};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU363036};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW   ECO:0000256|RuleBase:RU363036};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199418}.
SQ   SEQUENCE   364 AA;  41156 MW;  84C607713C238C8D CRC64;
     MRKVILTGDR PTGKLHVGHY VGSLRRRVEL QNSGEFDDIF IMIADAQALT DNAENPEKVR
     QNVIEVALDY LAVGLDPAKS TLFVQSQIPE LTELTFYYMN LVTVSRLQRN PTVKSEIQMR
     NFETSIPVGF FTYPISQAAD ITAFKATTVP VGEDQEPMIE QCREIVRKFN SVYGEALVEP
     NILLPDNAAC LRLPGTDGTA KMSKSLGNCI YLSESPEMIK KKVMGMFTDP NHLRVEDPGE
     VENNPVFIYL DAFAKDEHFA EFAPDYANLD EMKAHYKRGG LGDVKVKKFL NNVLQSELEP
     IRKRREEFQK DIPYVYDVIK KGSEVAEEVA AQTLSDVKKA MKIDYFSDEE LIAMQSAKYQ
     VTED
//