ID A0A1H7GPZ8_9GAMM Unreviewed; 403 AA.
AC A0A1H7GPZ8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=3-oxoacyl-[acyl-carrier-protein] synthase II {ECO:0000313|EMBL:SEK40233.1};
GN ORFNames=SAMN05216262_101272 {ECO:0000313|EMBL:SEK40233.1};
OS Colwellia chukchiensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Colwelliaceae; Colwellia.
OX NCBI_TaxID=641665 {ECO:0000313|EMBL:SEK40233.1, ECO:0000313|Proteomes:UP000199297};
RN [1] {ECO:0000313|Proteomes:UP000199297}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.9127 {ECO:0000313|Proteomes:UP000199297};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
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DR EMBL; FOBI01000001; SEK40233.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H7GPZ8; -.
DR STRING; 641665.GCA_002104455_00432; -.
DR OrthoDB; 9808669at2; -.
DR UniPathway; UPA00094; -.
DR Proteomes; UP000199297; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023160};
KW Reference proteome {ECO:0000313|Proteomes:UP000199297};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 2..403
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 403 AA; 42367 MW; 1F0B95AEB9785B9E CRC64;
MSDAIVVSGM GCISAAGNNV AQFCANLFQP TLANFIAPTL IQKPDENSYF LAAQVKDYYA
NEHFTKQQLK LLDPFAQFAL LSAEQAIADA KLAINASNQH RISVVHGTSI GGQETIEQAY
AQLFAQGKSR THPFTVPKLL PSSACGHIAM KYGIKGPTFA TSSACSSSGH AIAMATLMLR
SNLIDYAIVG GAEACLTPGN FYAWHGLRVL AHDSCRPFSK NRSGLVMGEG AASLVLERES
TAKNRGATCY AKLVGIGMSS DAHNIVQPLA QGAEQAMIAA LKDAELSPSD IDYINAHGSG
TTQNDTTESA AILSVFNDAN APFVSSTKGT HGHMLGAGAA LEAIAAILAL EKQTVPATAN
FVEKDPNCNI NLVANNKVAA KLSHVMSNSF AFGGLNTSLI FQR
//
