ID A0A1H7GVA6_9ACTN Unreviewed; 629 AA.
AC A0A1H7GVA6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Succinate dehydrogenase subunit A {ECO:0000313|EMBL:SEK42008.1};
GN ORFNames=SAMN05660976_00504 {ECO:0000313|EMBL:SEK42008.1};
OS Nonomuraea pusilla.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=46177 {ECO:0000313|EMBL:SEK42008.1, ECO:0000313|Proteomes:UP000198953};
RN [1] {ECO:0000313|EMBL:SEK42008.1, ECO:0000313|Proteomes:UP000198953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43357 {ECO:0000313|EMBL:SEK42008.1,
RC ECO:0000313|Proteomes:UP000198953};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOBF01000001; SEK42008.1; -; Genomic_DNA.
DR RefSeq; WP_055508331.1; NZ_FOBF01000001.1.
DR AlphaFoldDB; A0A1H7GVA6; -.
DR STRING; 46177.SAMN05660976_00504; -.
DR OrthoDB; 9805351at2; -.
DR Proteomes; UP000198953; Unassembled WGS sequence.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF89; SUCCINATE DEHYDROGENASE [IRON-SULFUR SUBUNIT] (SUCCINIC DEHYDROGENASE)-RELATED; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PIRSF; PIRSF000171; SDHA_APRA_LASPO; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000198953}.
FT DOMAIN 9..428
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 482..591
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT ACT_SITE 321
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000171-1"
SQ SEQUENCE 629 AA; 69450 MW; 674B54206FCD92D1 CRC64;
MEIERHEYDV VVIGAGGAGL RAAIEARQQG KRTAIVCKSL FGKAHTVMAE GGAAAAMGNV
NPDDNWMVHF RDTMRGGKFL NNWRMAELHA KEAPDRVWEL EAWGALFDRT KDGKISQRNF
GGHEYPRLAH VGDRTGLELI RTLQQRVVAL QQEDYETHGD HEAYIKVFAE CTVTRLLKDG
DRISGAFGYW RESGSFVLFD APAVVLATGG IGKSYVVTSN SWEYTGDGHA LALLAGAKLI
NMEFIQFHPT GMVWPPSVRG ILVTESVRGD GGVLRNSDGE RFMFNYIPEV FKDKYATTEE
EGDRWYTDQA NNRRPPELLP RDEVARAINA EVKAGRGSPQ GGVFLDVSTR LPAEEIRRRL
PSMYHQFKEL ADVDITAEPM QVGPTCHYIM GGVEVDADTG ASAVPGLFAA GEVSGGMHGS
NRLGGNSLSD LLVFGRRAGA GAAAYVDGLA ARPKLPQDQV DAAREEALAP LGRDGENPYE
VHHELQRTMN DLVGIIRKAE EVSEALEVVE KLKERVRLVG AGGSRIYNPG WHLAIDLRNM
VLVSECVARA ALMREESRGG HTRDDFPGMN PEWRRKLLVC SASDGSSVQV EERLQPRMRD
DLITLFDRDE LKKYLTDEEM AEFDGIAKS
//
