ID   A0A1H7M7R6_9FIRM        Unreviewed;       478 AA.
AC   A0A1H7M7R6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=DNA polymerase III alpha subunit {ECO:0000313|EMBL:SEL07233.1};
GN   ORFNames=SAMN02910377_02580 {ECO:0000313|EMBL:SEL07233.1};
OS   Pseudobutyrivibrio ruminis.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Pseudobutyrivibrio.
OX   NCBI_TaxID=46206 {ECO:0000313|EMBL:SEL07233.1, ECO:0000313|Proteomes:UP000182321};
RN   [1] {ECO:0000313|Proteomes:UP000182321}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ACV-9 {ECO:0000313|Proteomes:UP000182321};
RA   Varghese N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FNZX01000022; SEL07233.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H7M7R6; -.
DR   Proteomes; UP000182321; Unassembled WGS sequence.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   InterPro; IPR011708; DNA_pol3_alpha_NTPase_dom.
DR   InterPro; IPR040982; DNA_pol3_finger.
DR   InterPro; IPR004805; DnaE2/DnaE/PolC.
DR   PANTHER; PTHR32294; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR   PANTHER; PTHR32294:SF0; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR   Pfam; PF07733; DNA_pol3_alpha; 1.
DR   Pfam; PF17657; DNA_pol3_finger; 1.
PE   4: Predicted;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   Reference proteome {ECO:0000313|Proteomes:UP000182321};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          84..208
FT                   /note="Bacterial DNA polymerase III alpha subunit NTPase"
FT                   /evidence="ECO:0000259|Pfam:PF07733"
FT   DOMAIN          309..415
FT                   /note="DNA polymerase III alpha subunit finger"
FT                   /evidence="ECO:0000259|Pfam:PF17657"
SQ   SEQUENCE   478 AA;  54502 MW;  5744CE0902512A6D CRC64;
     MVKETKDIVL AKEYKFGEEY KKYIVTTQRV TDEGRTSLKV TDTSIFGGHD VGITIQEPIA
     YFSGLCEDGL LSGLVPDGKT ALEVLKDLCR RGFSERYPDA SADVYTRLTH EIEIIKQKGM
     VGGFLIIQDF IKYARSKNLM ISPGSGALPG CLVAYCLGIT RVDPIEESLS FERYLNIERE
     TPSYCIRIDV QRGGRSLIFE YLSEKYGSGM PGLLKMLDIS IKECVELSII KDAIDNNISS
     SKGRRIEIAG IDKNDPAVFE LLASDETEGI LYFDRYDPHT YTTWCRPDDN GNWHEYHVPL
     VTEDAVLFET IWPKTMDELM AAISLDRCLP EEHVGKYLHN IKNQQLITYE CSELEPILHT
     TYGCVIYQEQ VMLILQDIGG FSPEKSDLCR RLLSKRHHLA VEDYRVDFVN GAKEKTGIVA
     PVANAIYEVL WDEARYCFNK SHIASFSLMI YEMAWLKVYF RSEFMEAVEK YRGLKSEI
//