ID   A0A1H7MB70_9GAMM        Unreviewed;       744 AA.
AC   A0A1H7MB70;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   ORFNames=SAMN05216262_105161 {ECO:0000313|EMBL:SEL08148.1};
OS   Colwellia chukchiensis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Colwelliaceae; Colwellia.
OX   NCBI_TaxID=641665 {ECO:0000313|EMBL:SEL08148.1, ECO:0000313|Proteomes:UP000199297};
RN   [1] {ECO:0000313|Proteomes:UP000199297}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.9127 {ECO:0000313|Proteomes:UP000199297};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR   EMBL; FOBI01000005; SEL08148.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H7MB70; -.
DR   STRING; 641665.GCA_002104455_03014; -.
DR   OrthoDB; 6735159at2; -.
DR   Proteomes; UP000199297; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd09622; CBM9_like_HisKa; 1.
DR   CDD; cd00082; HisKA; 1.
DR   Gene3D; 1.10.287.130; -; 1.
DR   Gene3D; 2.60.40.1190; -; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR022510; Sortase_His-kinase.
DR   NCBIfam; TIGR03785; marine_sort_HK; 1.
DR   PANTHER; PTHR45436:SF5; SENSOR HISTIDINE KINASE TRCS; 1.
DR   PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF49344; CBD9-like; 1.
DR   SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SEL08148.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199297};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   TRANSMEM        428..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          448..503
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          511..744
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
SQ   SEQUENCE   744 AA;  83680 MW;  B06E894B2F73F0C9 CRC64;
     MKWRFGLRSK LLLLSGFLFA IPWFGYQYVW EMEKYLRYGQ EQTLVGTARA LATALHERDN
     LFNNQASFLP SVEKGKDLYS YGLSAPIQLD GLNNDWPDFA NKAHFYQQNN QLYQQLSAQE
     LSINLTAAVG TYGKYLYLYF SVVDDKVIYR DTNARSISHN DHIELAFINP NGVFSRFIIS
     NKTTGWIDAY RITDVAHNIP VPARQIQGHW RDTPQGYDVE VRVPLTEFND NIAFAVHDVD
     QPLGSIETSI GSADPSSPET LGTILVPSPE IERIVKGMSY TNSSIWVVDQ HHRVLASTGD
     IKNASGVWNK HVNLNNQLAN NDDSNILLTA WQTFESKILK PIYESILTQP PSNFIDQLYD
     SENLTGKHIE SALKGEPMSQ WRLTTDQKAV VLSAAYPVYI NEQVKGAVIV EETTNGIRTL
     RNQALEKLFS SIIVIMLLGA LAFFLFASRI SNRIRALSNQ AELAIDEHGR INGTVATSNS
     NDEIGDLTRS FSTAVNRLGQ YNHYLENMSS RLSHELRTPI AVVRTSLETL AMQQQANSAA
     LITASENSNA DNALTKQNPY LQRALQGVER LSLILTNINE ATRIEEILNH TEPSVFDLGQ
     VINGCMQGYR LIYPQINFTF KEVNRESYKV LGSPEHIAQL LDKVIANAVE FSEDDHVSVT
     VHNHQQVLSL TISNQGQLLP EQMSEQLFDS MVSIRDKHNN QQPHLGLGLY IARLICQFHH
     GSIKAQNNQR LSGVDVIITL PLHK
//