ID A0A1H7P0I8_9BURK Unreviewed; 622 AA.
AC A0A1H7P0I8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=SAMN05216359_10792 {ECO:0000313|EMBL:SEL28808.1};
OS Roseateles sp. YR242.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Roseateles.
OX NCBI_TaxID=1855305 {ECO:0000313|EMBL:SEL28808.1, ECO:0000313|Proteomes:UP000198631};
RN [1] {ECO:0000313|EMBL:SEL28808.1, ECO:0000313|Proteomes:UP000198631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YR242 {ECO:0000313|EMBL:SEL28808.1,
RC ECO:0000313|Proteomes:UP000198631};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; FOAV01000007; SEL28808.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H7P0I8; -.
DR STRING; 1855305.SAMN05216359_10792; -.
DR OrthoDB; 9760034at2; -.
DR Proteomes; UP000198631; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR01389; recQ; 1.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:SEL28808.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 31..207
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 228..378
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 549..622
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 622 AA; 69262 MW; DD6036E818E8D6DD CRC64;
MSPPKHHPVP INILQEVFGY SAFRGQQAEI VDHVTQGGDA LVLMPTGGGK SLCYQVPAIV
RQRAGHGVTV VVSPLIALMH DQVGALEEAG VHAAFLNSSQ SQEEAQHIER EMLAGRLSLL
YAAPERLNTP RFLAQLTSLH ERGLLSLFAI DEAHCVSQWG HDFRSEYLSL NLLHERFPDV
PRIALTATAD DITRADIIER LQLQDSRVFI ASFDRPNIRY LIVEKDKPKE QLLRFIQEDH
DGDAGVVYCQ SRKKVEETAE WLRAEGVSAL AYHAGMDSDI RRRHQDRFLR EDGIVMVATV
AFGMGIDKPD VRFVAHLDLP KNIEGYYQET GRAGRDGEAA QAWMAYGLAD VVNQRRMIDE
SPSTEEFKQV QRGKLDALLA LAEATDCRRQ RLLAYFGEES EPCGNCDNCL HAPATWDATE
SARMALSCIY RFRQNGGQRF GAGHLIDVLR GKETEKVRQY GHQHLSTWAI GASLGEQQWR
AVLRQLIALG HVVTEGEFHT ISLTESARAV LKGEVQLLLR QPTTPARKGK TSRTGTSGKR
ATLVDPELAP DAQFRFNSLK AWRAEVAREH GLPAYVIFQN VTLAEMARQH PRSLEELSGI
SGVGAKKLEA YGEDLLRVLG AH
//
