ID A0A1H7S8J6_9ACTN Unreviewed; 308 AA.
AC A0A1H7S8J6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=5'-3' exonuclease {ECO:0000313|EMBL:SEL68855.1};
GN ORFNames=SAMN04515665_11719 {ECO:0000313|EMBL:SEL68855.1};
OS Blastococcus sp. DSM 46786.
OC Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC Geodermatophilaceae; Blastococcus.
OX NCBI_TaxID=1798227 {ECO:0000313|EMBL:SEL68855.1, ECO:0000313|Proteomes:UP000198952};
RN [1] {ECO:0000313|Proteomes:UP000198952}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 46786 {ECO:0000313|Proteomes:UP000198952};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOAO01000017; SEL68855.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H7S8J6; -.
DR STRING; 1798227.SAMN04515665_11719; -.
DR Proteomes; UP000198952; Unassembled WGS sequence.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR CDD; cd09898; H3TH_53EXO; 1.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR020045; DNA_polI_H3TH.
DR InterPro; IPR038969; FEN.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR Pfam; PF01367; 5_3_exonuc; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SMART; SM00279; HhH2; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Exonuclease {ECO:0000313|EMBL:SEL68855.1};
KW Hydrolase {ECO:0000313|EMBL:SEL68855.1};
KW Nuclease {ECO:0000313|EMBL:SEL68855.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198952}.
FT DOMAIN 1..273
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 308 AA; 31727 MW; 211B9557C82314B4 CRC64;
MTTMLLDAAS LYFRAFYGVP TSVTTPDGRP INAVRGFLDM TARLVTAHGP DRLVACWDDD
WRPAFRVAAL PSYKAHRLAP DGGEETPDEL VPQVPVLVEV LAAAGIARVG APGYEADDVI
GTLATRARGP VDVVTGDRDL FQLVDDARGV RVLYTARGIS DLEYVDEAAV AAKYGIPGRA
YADFAVLRGD PSDGLPGVAG VGAKTAAALI GGFGDLAGIR AAVARTVVPA PPLTAAVLKK
LHAAADYLDA APVVVAVARD VDLPAVEGTL PRSPADPGAL AALAERHGLQ SSLGRLGAAL
GWPADALG
//
