ID A0A1H7TF38_9SPHI Unreviewed; 378 AA.
AC A0A1H7TF38;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:SEL83004.1};
GN ORFNames=SAMN05421740_1117 {ECO:0000313|EMBL:SEL83004.1};
OS Parapedobacter koreensis.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Parapedobacter.
OX NCBI_TaxID=332977 {ECO:0000313|EMBL:SEL83004.1, ECO:0000313|Proteomes:UP000198916};
RN [1] {ECO:0000313|EMBL:SEL83004.1, ECO:0000313|Proteomes:UP000198916}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Jip14 {ECO:0000313|EMBL:SEL83004.1,
RC ECO:0000313|Proteomes:UP000198916};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
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DR EMBL; FNZR01000011; SEL83004.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H7TF38; -.
DR STRING; 332977.SAMN05421740_1117; -.
DR Proteomes; UP000198916; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08281; liver_ADH_like1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43880; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR43880:SF12; ALCOHOL DEHYDROGENASE CLASS-3; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..375
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 378 AA; 39622 MW; 0B082919F4E9CE01 CRC64;
MSIKIKAAVL HSMGSERPYD QSKPLVIEEL TLAPPREGEV LVRIRAAGLC HSDLSVIDGN
RPRQMPMVLG HEAAGEVVEL GPGISDLAVG DHVVFSFVPV CGHCMPCMTA RPALCENGVK
ANNGGVLLGG GIRLQDRGQH AVHHHMGVSA FAEYTVTSRK SVVRVDRTLP FEIAALFGCA
VMTGVGAVVN TAKLSMGQTV LITGMGGIGF SALLGALASG AGRIIVADVN AEKLALAKQL
GADEAVDASR ADAVQQVHDI TGGGVDIGLD FTGVVPALEF TYQATARGGK TVTAGLPHPS
RMMQLSPTKL VAEERMLLGS YLGGCIPARD IPAYIALHQA GRLPVDKLLT HTLGLHEINE
GFERLAKGEA IRQVITFS
//
