ID   A0A1H7VGC5_9ACTN        Unreviewed;       714 AA.
AC   A0A1H7VGC5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=DNA helicase IV {ECO:0000313|EMBL:SEM07847.1};
GN   ORFNames=SAMN04515665_12918 {ECO:0000313|EMBL:SEM07847.1};
OS   Blastococcus sp. DSM 46786.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Blastococcus.
OX   NCBI_TaxID=1798227 {ECO:0000313|EMBL:SEM07847.1, ECO:0000313|Proteomes:UP000198952};
RN   [1] {ECO:0000313|Proteomes:UP000198952}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 46786 {ECO:0000313|Proteomes:UP000198952};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOAO01000029; SEM07847.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H7VGC5; -.
DR   STRING; 1798227.SAMN04515665_12918; -.
DR   OrthoDB; 9787585at2; -.
DR   Proteomes; UP000198952; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR027351; (+)RNA_virus_helicase_core_dom.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF01443; Viral_helicase1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000198952}.
FT   DOMAIN          194..594
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         215..222
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   714 AA;  76935 MW;  846DC2F908577CCB CRC64;
     MPVSTRAFDL PPQLAAKAEP ALIAADEQHF TLIADSLARS IAELTERLAA ERAGPGGTGQ
     AALDRDLEVH RLATRLRTLR RFGLDLCLGR IVPADGGEPV RVGRLGLTDG AGRRLLVDWR
     SPAAEPFFAA THADPMGLVS RRRYRWTRGR ITDYWDEVFT PDGLEGHAAL DDQSAFLASL
     GGNRSARMRD VLGTIQADQD AIIRAGSRGA LVVDGGPGTG KTVVALHRAA YLLYSDPRLG
     HCGGGVLFVG PHEPYLAYVA DVLPGLGEEG VRTCTLRDLV PEGAGALPEA DPDVARLKAS
     VGMVAAIEAA VRFYEEPPAR GTTVTTPWDD VRLTAEDWAE AFDAAEPGTP HNEAREQVWE
     TLLEIVVDAH DADVEPDLIR AAAGQDRELR TAFDRAWPLL DPDDLVGDLW SVPAYLRRCA
     PGLAPDEVRR LQRSDPRAWT VADLPLLDAA RMRLGDAGAV RRRQREAAVV ARERERMSAV
     IDELIAADDS ELLLMTSLRH GDLRDALVDQ DALPAVDADP LAGTFAHVVV DEAQELTDAE
     WQVLLRRCPS RSFTVVGDRA QARRGFPEPW AERLHRVGLT EVRQMSLTVN YRTPAEVVAA
     AEPVIRAVLP DANVPTSVRS TGVPVAHGSV AELGAVVDGW LAGHAEGIGC VIGAPSFAER
     PRVRSLTPSL AKGLEFDLVV LVDPESFGAG VGGAVDRYVA MTRATQQLVV LTSR
//