ID   A0A1H7VIU9_9GAMM        Unreviewed;       977 AA.
AC   A0A1H7VIU9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase {ECO:0000313|EMBL:SEM09176.1};
GN   ORFNames=SAMN05428989_3024 {ECO:0000313|EMBL:SEM09176.1};
OS   Pseudoxanthomonas sp. GM95.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Pseudoxanthomonas.
OX   NCBI_TaxID=1881043 {ECO:0000313|EMBL:SEM09176.1, ECO:0000313|Proteomes:UP000199164};
RN   [1] {ECO:0000313|Proteomes:UP000199164}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GM95 {ECO:0000313|Proteomes:UP000199164};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOAX01000003; SEM09176.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H7VIU9; -.
DR   STRING; 1881043.SAMN05428989_3024; -.
DR   Proteomes; UP000199164; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd00130; PAS; 1.
DR   CDD; cd12915; PDC2_DGC_like; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 4.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 2.
DR   SMART; SM00091; PAS; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        266..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          382..433
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          434..478
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          582..712
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          721..975
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   977 AA;  108007 MW;  CD81D2B34EF03E2F CRC64;
     MLRFGLLLAA ALAIGLGYWV VSDRRNRLEG AERQSQALVA GLERVITLEL RNIERAMGGI
     SSDAHQLMAS VPDQAPRLIS ESIAGVVSRH HEIQSIVLVD HDGTALTTGQ GDPGFAGWID
     AAAHGDRNPL RFGQPYALAS GRWVLPIALP MPADGDEAPS HWLLTRLYTD ELQAMVDGLD
     TGRDGLASVV GPGDVLLARS LASANNVVGR HVAGPSSEEL HNDGTLIPER TSEIDGLRRV
     VAVRLLKPYP LQVWAGLSTR EALVPWFKFV GAALVLYLLY WAMLLVMLRA VRRADRDQRE
     LLHHIQRNSE HLRLAQHTGK VGAWALEHGS GHLAWGGDIS SMFGLGGEET SSLRSFGRHV
     HLQDRGMLWQ RFVSAWRSRS AFSSEFRLVS DDGTERWVVA RGGVVEDDHG HLRMTGTLVD
     ISERMEAMSR VTDAERQFRL IFDRNPLPFW VHDARTQRFL EVNRAASLQY GFSREEFLTM
     QLRDICPGGL REPGQLIQGA AAGFDDAHVS QHRRKDGSTL QARIHGSEIR FGGQDARLVL
     AEDVSERIEY EKELAYRARH DQTTGLINVQ TLSDRLDQGV YPGYQVVYLQ LRGLQPIRDS
     LGRETADNVL RTLAARLQQW ADDFGLAAHQ PDEDFVLAIV HPHHAAAAIE AAIEAVREPI
     GDSDGSMQRL DARFGLAEED GSGQRAERII DNAALAAHAL ESAAFEIARY DGALARRYSD
     RLRMAARLRT AIEQNEFELH FQPIVRVADG SVAALEALVR WPQRDGTDIP PNEFIPLCED
     TGLIVPLGSW ILRRAAQAQA WLKRQGCGDL PVAVNVSAVQ MLQADLAGEL ELACTQAGIS
     PLALHMELTE TVLMNRPEQG MAIMQRLRDA GVCISLDDFG TGFSSMSYLR HLPLSSIKLD
     RTFVCDVDRD PRNASICRAL LQLGHSLGLV MIAEGVERPE ELEWLQRHGC DQVQGYLLGR
     PQPLELALQR VQGVAAR
//