ID A0A1H7VN86_9BURK Unreviewed; 799 AA.
AC A0A1H7VN86;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Histidine kinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=SAMN05192542_12623 {ECO:0000313|EMBL:SEM10349.1};
OS Paraburkholderia caballeronis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=416943 {ECO:0000313|EMBL:SEM10349.1, ECO:0000313|Proteomes:UP000199120};
RN [1] {ECO:0000313|Proteomes:UP000199120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 26416 {ECO:0000313|Proteomes:UP000199120};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FOAJ01000026; SEM10349.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H7VN86; -.
DR STRING; 416943.SAMN05445871_4335; -.
DR OrthoDB; 9803176at2; -.
DR Proteomes; UP000199120; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00088; HPT; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.20.120.160; HPT domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR024478; HlyB_4HB_MCP.
DR InterPro; IPR036641; HPT_dom_sf.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR008207; Sig_transdc_His_kin_Hpt_dom.
DR PANTHER; PTHR43395:SF10; CHEMOTAXIS PROTEIN CHEA; 1.
DR PANTHER; PTHR43395; SENSOR HISTIDINE KINASE CHEA; 1.
DR Pfam; PF12729; 4HB_MCP_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF01627; Hpt; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47226; Histidine-containing phosphotransfer domain, HPT domain; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50894; HPT; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00110}; Reference proteome {ECO:0000313|Proteomes:UP000199120};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 207..260
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 351..403
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 414..521
FT /note="HPt"
FT /evidence="ECO:0000259|PROSITE:PS50894"
FT MOD_RES 459
FT /note="Phosphohistidine"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00110"
SQ SEQUENCE 799 AA; 87134 MW; F6DD54BECBE514DB CRC64;
MTIRHRITLL VVLMFVALMS IGGYAVYQTR RSATEVRSVT QGVVPSALAS ADLVSQLKDV
QLATMTLVYA PDVNMVSQAQ DELKAKQKTL SDALDVQGSA AASHAQVGLV AQARESLANY
FSAIADTAKM KAEGKNEMAQ AFLFANVAQY RDELEGIVTT LRVEKNRQKD DAIKSLNDML
STTTSAIAGV TGGAVLLLTV IGLLLYRQIT QPLTRMQSMM SEIASNQDFT RRVPVGRMDE
IGHSIVAFNG MIEKIQQSSA QLKRKTADIQ AMLQNMQQGI LTIVDGAQIH AEYSAYLEAI
FETNEIAGQP VMDLVFSHTD LDANALSQVD AAIYACLGED SINFAFNQHL LVNEITRTMP
DGRKKILDLS WSAITDETDT VVRLMLCVRD VTELRELAAE AGEQKRQLEM IGEILSVSEE
KFHHFVESST SFIQQNERII SQDACPDSAA IAELFRNMHT IKGNARTYRF QHLTGVAHEA
EQRYDALRRG EPLDDGGWDP QALIDDLARV KEALTHYATI NEVSLGRKSA SQAGLDTSRF
VPVEREAIDA SLRQIEHADV SDLKSMQAMR EAVRHTLRLF GTERVDDMLS GVLDSLPSLA
KELGKAEPVV RIDDHGYRLR SEAGPTLTNV FVHLLRNSID HGIEKPDERA VVAKPSAGTI
LLDVNVASGD GTLQITLGDD GRGLALARIR GIAVERGWID ADAEIADEEV AEFIFRSGFS
TASAVTDVSG RGVGMDAVRD FLTREGGRIA LHFVDGKRGA AYRRFETIVT LPGRWAVGTA
GLAPAPVRAA GASQAETLA
//
