ID   A0A1H7WEW7_9RHOB        Unreviewed;       232 AA.
AC   A0A1H7WEW7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=pre-crRNA processing endonuclease {ECO:0000256|PIRNR:PIRNR029950};
DE            EC=3.1.-.- {ECO:0000256|PIRNR:PIRNR029950};
GN   ORFNames=SAMN05443999_11536 {ECO:0000313|EMBL:SEM19884.1};
OS   Roseovarius azorensis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Roseovarius.
OX   NCBI_TaxID=1287727 {ECO:0000313|EMBL:SEM19884.1, ECO:0000313|Proteomes:UP000199582};
RN   [1] {ECO:0000313|EMBL:SEM19884.1, ECO:0000313|Proteomes:UP000199582}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 100674 {ECO:0000313|EMBL:SEM19884.1,
RC   ECO:0000313|Proteomes:UP000199582};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: CRISPR (clustered regularly interspaced short palindromic
CC       repeat) is an adaptive immune system that provides protection against
CC       mobile genetic elements (viruses, transposable elements and conjugative
CC       plasmids). CRISPR clusters contain spacers, sequences complementary to
CC       antecedent mobile elements, and target invading nucleic acids. CRISPR
CC       clusters are transcribed and processed into CRISPR RNA (crRNA).
CC       {ECO:0000256|PIRNR:PIRNR029950}.
CC   -!- SIMILARITY: Belongs to the CRISPR-associated protein Cas5 family.
CC       Subtype I-C/Dvulg subfamily. {ECO:0000256|PIRNR:PIRNR029950}.
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DR   EMBL; FOAG01000015; SEM19884.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H7WEW7; -.
DR   STRING; 1287727.SAMN05443999_11536; -.
DR   OrthoDB; 5621871at2; -.
DR   Proteomes; UP000199582; Unassembled WGS sequence.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-UniRule.
DR   GO; GO:0043571; P:maintenance of CRISPR repeat elements; IEA:UniProtKB-UniRule.
DR   CDD; cd09752; Cas5_I-C; 1.
DR   Gene3D; 3.30.70.2660; -; 1.
DR   InterPro; IPR021124; CRISPR-assoc_prot_Cas5.
DR   InterPro; IPR013422; CRISPR-assoc_prot_Cas5_N.
DR   InterPro; IPR010155; CRISPR-assoc_prot_Cas5d.
DR   NCBIfam; TIGR01876; cas_Cas5d; 1.
DR   NCBIfam; TIGR02593; CRISPR_cas5; 1.
DR   Pfam; PF09704; Cas_Cas5d; 1.
DR   PIRSF; PIRSF029950; Cas_CT1134; 1.
PE   3: Inferred from homology;
KW   Antiviral defense {ECO:0000256|ARBA:ARBA00023118,
KW   ECO:0000256|PIRNR:PIRNR029950};
KW   Endonuclease {ECO:0000256|PIRNR:PIRNR029950};
KW   Hydrolase {ECO:0000256|PIRNR:PIRNR029950};
KW   Nuclease {ECO:0000256|PIRNR:PIRNR029950};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199582};
KW   RNA-binding {ECO:0000256|PIRNR:PIRNR029950}.
SQ   SEQUENCE   232 AA;  25688 MW;  D01B9C5EFD39B69A CRC64;
     MAYGIRLHVW GQHGLFTRPE LKVERVSYDV ITPSAARGIL EAIHWKPAIC WVIDSIHVLE
     PIRFQSIRRN EVGHKAPAGT IKRAVNRGDM QGVQILVDED RQQRASTVLV GPRYVIEAHF
     VLTARAEASE TEGKHLDIFN RRAAKGQCFH QPCLGAREFA AGFELVPPGA PLPARNAQAE
     TPDLGFGAPR DLGYMLWDID HAAPGRPSLL FRASLQDGVM EVPQPGSPEV KR
//