ID   A0A1H7XV46_9ACTN        Unreviewed;       522 AA.
AC   A0A1H7XV46;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Maltose/maltodextrin transport system permease protein {ECO:0000256|RuleBase:RU367050};
GN   ORFNames=SAMN05660976_04979 {ECO:0000313|EMBL:SEM37555.1};
OS   Nonomuraea pusilla.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Nonomuraea.
OX   NCBI_TaxID=46177 {ECO:0000313|EMBL:SEM37555.1, ECO:0000313|Proteomes:UP000198953};
RN   [1] {ECO:0000313|EMBL:SEM37555.1, ECO:0000313|Proteomes:UP000198953}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43357 {ECO:0000313|EMBL:SEM37555.1,
RC   ECO:0000313|Proteomes:UP000198953};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the ABC transporter complex MalEFGK involved in
CC       maltose/maltodextrin import. Probably responsible for the translocation
CC       of the substrate across the membrane. {ECO:0000256|RuleBase:RU367050}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363032};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. MalFG subfamily. {ECO:0000256|ARBA:ARBA00009047,
CC       ECO:0000256|RuleBase:RU367050}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FOBF01000012; SEM37555.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H7XV46; -.
DR   STRING; 46177.SAMN05660976_04979; -.
DR   OrthoDB; 34224at2; -.
DR   Proteomes; UP000198953; Unassembled WGS sequence.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0055085; P:transmembrane transport; IEA:UniProtKB-UniRule.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.20.58.370; MalF N-terminal region-like; 1.
DR   Gene3D; 3.10.650.10; MalF N-terminal region-like; 1.
DR   Gene3D; 1.10.3720.10; MetI-like; 1.
DR   InterPro; IPR035277; MalF_N.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   InterPro; IPR032550; TM_PBP2_N.
DR   PANTHER; PTHR47314; MALTOSE/MALTODEXTRIN TRANSPORT SYSTEM PERMEASE PROTEIN MALF; 1.
DR   PANTHER; PTHR47314:SF1; MALTOSE_MALTODEXTRIN TRANSPORT SYSTEM PERMEASE PROTEIN MALF; 1.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   Pfam; PF16296; TM_PBP2_N; 1.
DR   SUPFAM; SSF160964; MalF N-terminal region-like; 1.
DR   SUPFAM; SSF161098; MetI-like; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU367050};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198953};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW   ECO:0000256|RuleBase:RU367050};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363032};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363032};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363032}.
FT   TRANSMEM        21..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   TRANSMEM        50..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   TRANSMEM        80..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   TRANSMEM        287..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   TRANSMEM        327..347
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   TRANSMEM        377..399
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   TRANSMEM        420..443
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   TRANSMEM        489..511
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363032"
FT   DOMAIN          292..510
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS50928"
SQ   SEQUENCE   522 AA;  55651 MW;  FCF941A317C351E6 CRC64;
     MTLDVREAAE TREAPRPRRE VTTAFVVSRI AVLAVTAAVL LYAAPPLVAS RSWAALAVLA
     VTAAVLAFLY LTRRFIPAKY LIPGTVFLIA FQVFPVLYTV STAFTNFGDG HRGDKASAIT
     AIETGSVRQA PGSPEYSLTV ALRDGEMVFL LVDPKTKQVS LGTGEGLTGL SGAQVGVTGK
     VLSAPGLTVL KAPEAAARAQ EVSALAVPTR GGVIKANGLS RAVEGRAALT YDAACDCVKG
     EGDVWKADES QGYFVNAKGE HLAQGWQVNV GFANFARVLT NPTISGYFAG VFGWNLVFAL
     ASVAGTFALG MSVALALHHP RMRGTKAYRI ALILPYAMPA FAMLLVWRDM FNRDFGLINQ
     FFGLDVDWLG QPSTARLAVI LVNLWLGFPY MFLVTTGALQ AIPRELTEAA SIDGATPWKA
     FRSVTLPLLL VALTPLLISS FAFNFNNFNA IALTTEGGPF PAESPQVGST DLLITYTFRL
     AFGTGGAQFG FAAAISVFIF AIVAVISAVA FRRTRRQEEV YA
//