ID   A0A1H7YBI1_9FIRM        Unreviewed;       496 AA.
AC   A0A1H7YBI1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   ORFNames=SAMN04488698_103148 {ECO:0000313|EMBL:SEM42549.1};
OS   Candidatus Frackibacter sp. WG12.
OC   Bacteria; Bacillota; Clostridia; Halanaerobiales; Halobacteroidaceae;
OC   Frackibacter.
OX   NCBI_TaxID=2017977 {ECO:0000313|EMBL:SEM42549.1, ECO:0000313|Proteomes:UP000199298};
RN   [1] {ECO:0000313|Proteomes:UP000199298}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WG12 {ECO:0000313|Proteomes:UP000199298};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR   EMBL; FOCA01000003; SEM42549.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H7YBI1; -.
DR   OrthoDB; 446411at2; -.
DR   Proteomes; UP000199298; Unassembled WGS sequence.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd00082; HisKA; 1.
DR   Gene3D; 1.10.287.130; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR   PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   Pfam; PF13426; PAS_9; 2.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:SEM42549.1};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Transferase {ECO:0000313|EMBL:SEM42549.1};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   DOMAIN          278..494
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
SQ   SEQUENCE   496 AA;  56444 MW;  A2A962E0B9009EBB CRC64;
     MNIRKFKEIT LNIETLDNNE VNFRTKDEMI NLDTKTIVND FPGVAFALDN KSRLVAVNNR
     FCECLEDTRA GLLGKKLSDL NLGIDWDKLS LKETLRTGKP TYGYRNNLFI DYDYQLIYCN
     LPINLDTGEI GVLVLGIEVI MNSNFKETKI MNFNENTKIT DVWIVDDKCC YVDVTDPYNK
     FKVSSEELIG KKFTNVFPVE YDPLLSEAIE ENRLLESMRI LNTGKEKIYM QVIAFPLVID
     GEVVGGIDIL IDLNSKTRIV NQAYQANEIK NTGEMAFRII HELRNPLQVT KSSAELGSLL
     AQKENVNSEE IELYFNKIKD KVTEVNSLLN QLLEFSQPDK LVLKEVKIKG LLESLEEFLT
     KYCSKYKIDF QIEVTEEILK VEGDYELLER ALFNISKNAI EALQDYDGDR KIIVKCCKVN
     NDALISISNT GPTISNDIKD NIFAPFTSTK GINGAGLGLS VAYHIAHNLH EGKLWFKNKE
     EVGPTFYLSL PTLNNL
//