ID A0A1H7ZZK9_9BACT Unreviewed; 438 AA.
AC A0A1H7ZZK9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=MFS transporter, NHS family, nucleoside permease {ECO:0000313|EMBL:SEM64112.1};
GN ORFNames=SAMN04487902_102120 {ECO:0000313|EMBL:SEM64112.1};
OS Prevotella sp. ne3005.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=1761887 {ECO:0000313|EMBL:SEM64112.1, ECO:0000313|Proteomes:UP000199132};
RN [1] {ECO:0000313|Proteomes:UP000199132}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NE3005 {ECO:0000313|Proteomes:UP000199132};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FOCK01000002; SEM64112.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H7ZZK9; -.
DR STRING; 1761887.SAMN04487902_102120; -.
DR OrthoDB; 9783013at2; -.
DR Proteomes; UP000199132; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004740; Nuc_H_symport.
DR PANTHER; PTHR23522; BLL5896 PROTEIN; 1.
DR PANTHER; PTHR23522:SF4; NUCLEOSIDE PERMEASE NUPG-RELATED; 1.
DR Pfam; PF03825; Nuc_H_symport; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199132};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 233..438
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 438 AA; 48449 MW; 358A47CCFF03469B CRC64;
MNLKFRLSLM NFLEFAVWGA YLTCMGNYLG IAGLGDKISW FYAIQGIVSI FMPTLMGIVA
DKYMQPQRAL GLCHLLAGGF MLGCWWLGIQ AGFGNELENK ALFIALYTLS VAFYMPTIAL
TNTTAFTILK KNGLDTVKDF PPIRVLGTVG FIVMMWFVNC AVWEDGGFSM TLSDNAHKFQ
YTYMQFFVSG VLSIVLFLYC FTLPECKLEK KETNVSLAES LGLNAFKLFK SQKMALFFIF
SALLGMCLQV TNGYAGPFIT SFKGSADAAI ATSFAANNAT LLTSISQISE ALCILMIPFF
LKRFGIKVVM LMSMFAWVFR FGFFGVGNPA MPGVIMFILS CIVYGVAFDF FNVSGGIFVD
QECEPSVKAS AQGLFMMMTN GVGATFGTLV AGEIVNHYCH WENGFLQGDW TTCWFIFATF
ALVVGISFAL VFHPEKTK
//
