ID   A0A1H8AG55_STIAU        Unreviewed;      1457 AA.
AC   A0A1H8AG55;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Nonribosomal peptide synthetase MxcG {ECO:0000313|EMBL:SEM68914.1};
GN   ORFNames=SAMN05444354_12130 {ECO:0000313|EMBL:SEM68914.1};
OS   Stigmatella aurantiaca.
OC   Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC   Archangiaceae; Stigmatella.
OX   NCBI_TaxID=41 {ECO:0000313|EMBL:SEM68914.1, ECO:0000313|Proteomes:UP000182719};
RN   [1] {ECO:0000313|Proteomes:UP000182719}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17044 {ECO:0000313|Proteomes:UP000182719};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOAP01000021; SEM68914.1; -; Genomic_DNA.
DR   RefSeq; WP_075009957.1; NZ_FOAP01000021.1.
DR   OrthoDB; 9757540at2; -.
DR   Proteomes; UP000182719; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR   GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR   CDD; cd05930; A_NRPS; 1.
DR   CDD; cd05235; SDR_e1; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.980; -; 2.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR013120; Far_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR010080; Thioester_reductase-like_dom.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR   NCBIfam; NF038078; NRPS_MxcG; 1.
DR   NCBIfam; TIGR01746; Thioester-redct; 1.
DR   PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   Pfam; PF00668; Condensation; 1.
DR   Pfam; PF07993; NAD_binding_4; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SMART; SM00823; PKS_PP; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS50075; CARRIER; 1.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000182719}.
FT   DOMAIN          974..1049
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
SQ   SEQUENCE   1457 AA;  156026 MW;  D7D668D627A01BD6 CRC64;
     MRDSQETRQP LSAAQHGIWL GQQLDLKSPV YNAGECIEIL GAVDPALFEA AVRQAVREAE
     ALHVRFVNGE SGPQQVLGSQ TDWALHLADV SGAADPWAEV QAWMKVDLSR TVELSQGPLF
     AHALLKAGPQ RFFWFQRAHH IALDGFGFSL MARRVAEVYT AKAAGRPVTG GFGPFQAVLD
     EDVAYRNGPQ SALDRAFWTE RFADRPSPVS LASPAPMSST FVRQTRVLPP QMMERLQAAS
     KTAGLSWPDL MLAATAVYLH RLTDAAEVVL GLPVMNRLGT AALRVPSMAM NIVPLRVPVR
     PEASLLDVAR GVAAEVRAMR PHLRYRYEQL RRDLKLVGGQ RRLFGPVVNI MPFDYALRFA
     GMPTVAHNIS AGPVEDLSIG LYARSDGQGM RMDFDANPAC YEAQDLNAHQ GAFVELLEAL
     AAEPGLAVGQ AKTPATRRLP SAASTDADAL ASSVLDGGPL PVPARPVLEL ITQRAHETPD
     AIAVEHGQHQ LSYRDLLQHA QALSAQLVQE GVQPNTPVAV MLPRGLDAIV ASLGVLFSGA
     GYLPLDPQGP SSRTAAILED AKPTLILQRA SSEADPMARG NIVLRRNEAA PAAAPAPVQT
     EGERLAYVIY TSGSTGQPNG VQITQDALAH FVAGATHRYG VQRGDRVLQF APLHFDASVE
     EIFLTLCAGA KLVLRTEEML QSVSRLLDAC AEHGITVLDL PTAFWHELAY SVSTGAARLP
     PSIRLVIIGG EAALPERVAR WRAAAGSEVL LLNTYGPTEA TVVATTATLS GPPSAGAPEE
     EIPIGRPLPG VRTALIDAQG KLAAPGTEGE LYLLGGGLAR GYLGRPELNA ARFTSLGVLP
     GNPRAYRTGD KARVRADGQL VFAGRVDDEF KISGHRIDPT EIETVLLAHA GVRDAAVVGQ
     ILPGGTRRLC AHIVAGTPAP ASAELRRHLL AELPAAMVPS AFVFSERLPR TSTGKVDRNA
     LRLVMPPEDT GATAATTGFE RLVLQVWEQV LGLSGMSAQD DFFELGGQSL QTIQVANRLG
     VALGREVPVA TVFRYPTAAA LAQALEHGEQ NGTEGGGLSA AMLADAELPE DCVPWFQKPG
     TPAAPVPSPS TPWRQVLLTG ATGFVGAHLL DQLLRQTQAR VICLVRARDE AHAMERLRES
     MAGQRLSTAS LSERVMAVPA DLGQPWLGLS SARFHSLAAE CDALIHNAAV VSVVREYGSL
     QATNVRGTRE LLRLAAAVKP KPLHYVSTVA VAPQANLSPE VPEAFVPAHP GLRDGYQQSK
     WVAERLMEQA SVRGLPVSVY RLGRVSGAVD SGIVNPQDLV WRILLAGIPA GTLPQLDVGE
     VWTPVDYVAS ALVRLSLVSP GGGVFNLTPV PEVRLPDVFG WVRDYGYPVE LSPLPEWRTR
     VAQAQGSADS STTLAFFDLR AGASEPTFGL GTLRSERVLH ALSGSGLSCH RTERQLFHRY
     LDYCVEQGLL QRPPKHR
//