ID   A0A1H8B1X6_9PROT        Unreviewed;       684 AA.
AC   A0A1H8B1X6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN   Name=flhA {ECO:0000256|RuleBase:RU364093};
GN   ORFNames=SAMN05216325_10228 {ECO:0000313|EMBL:SEM76128.1};
OS   Nitrosomonas marina.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=917 {ECO:0000313|EMBL:SEM76128.1, ECO:0000313|Proteomes:UP000199459};
RN   [1] {ECO:0000313|EMBL:SEM76128.1, ECO:0000313|Proteomes:UP000199459}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nm22 {ECO:0000313|EMBL:SEM76128.1,
RC   ECO:0000313|Proteomes:UP000199459};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC       apparatus. Together with FliI and FliH, may constitute the export
CC       apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC       pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC       ECO:0000256|RuleBase:RU364093}.
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DR   EMBL; FOCP01000002; SEM76128.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8B1X6; -.
DR   STRING; 917.SAMN05216326_11526; -.
DR   Proteomes; UP000199459; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR   Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR   Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR   InterPro; IPR042194; FHIPEP_1.
DR   InterPro; IPR042193; FHIPEP_3.
DR   InterPro; IPR042196; FHIPEP_4.
DR   InterPro; IPR025505; FHIPEP_CS.
DR   InterPro; IPR006301; FlhA.
DR   InterPro; IPR001712; T3SS_FHIPEP.
DR   NCBIfam; TIGR01398; FlhA; 1.
DR   PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR   PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR   Pfam; PF00771; FHIPEP; 1.
DR   PIRSF; PIRSF005419; FlhA; 1.
DR   PRINTS; PR00949; TYPE3IMAPROT.
DR   PROSITE; PS00994; FHIPEP; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW   Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU364093};
KW   Cell projection {ECO:0000313|EMBL:SEM76128.1};
KW   Cilium {ECO:0000313|EMBL:SEM76128.1};
KW   Flagellum {ECO:0000313|EMBL:SEM76128.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW   Protein transport {ECO:0000256|RuleBase:RU364093};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU364093};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT   TRANSMEM        9..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        33..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        58..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        110..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        196..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        238..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
FT   TRANSMEM        268..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU364093"
SQ   SEQUENCE   684 AA;  73561 MW;  55058ABA727BA5A1 CRC64;
     MTGNNLKALA GPILIIMILG MMVLPLPPFI LDVLFTFNIA LAIIVLMVSL YTRNPLDFAV
     FPTVLLITTL LRLSLNVAST RVVLLEGHTG PDAAGKVIEA FGHFLVGGNY AVGLVVFIIL
     VVINFVVITK GAGRIAEVSA RFTLDAMPGK QMAIDADLNA GLIGEEEARN RRSAISKEAD
     FFGSMDGASK FVRGDAIAGV MVMLITIIGG LVVGMLQHDL DLDTAARNYT LLTIGDGLVA
     QIPALVISTA AGLVVSRVTT DEDLSEQVLG QLFTQPQVLV ITASILAVMG LVPGMPHFVF
     LLLASTLGLG AYFMIKSAQE SEAEQTEPAA VPVIEQQDAS WDDVTPIDTL GLEVGYRLIP
     LVDKAQQGDL LKRINGIRRK FAQDIGFLPP VVHIRDNLEL RPNAYQITLK GSVIGQGESY
     NGMYLAINPG RVTITLPGTP TSDPAFGLPA VWIEASLREQ AQANGYTVVD ASTVVTTHIN
     HLIHSHASEL LGRQELQLLL DHLSAKSPKL IEDLIPKLLP LSSVQKVLQN LLMENVHIRD
     MRTIIDVLTE HSPATQDAVQ LTAYVRAALG RAIVEQFFPA NTELQVISLH HELENILMQV
     VQTSGKEGGG IEPGLADMLL KEAAAAANQQ EKQGLPAVIL VPGPIRNLLS HFLRRAVPQI
     RVLAHAEVPD TRKIKVTSLI GGKS
//