ID   A0A1H8B454_9BACT        Unreviewed;       424 AA.
AC   A0A1H8B454;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Putative DNA modification/repair radical SAM protein {ECO:0000313|EMBL:SEM76868.1};
GN   ORFNames=SAMN04487902_103170 {ECO:0000313|EMBL:SEM76868.1};
OS   Prevotella sp. ne3005.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=1761887 {ECO:0000313|EMBL:SEM76868.1, ECO:0000313|Proteomes:UP000199132};
RN   [1] {ECO:0000313|Proteomes:UP000199132}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NE3005 {ECO:0000313|Proteomes:UP000199132};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOCK01000003; SEM76868.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8B454; -.
DR   STRING; 1761887.SAMN04487902_103170; -.
DR   Proteomes; UP000199132; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd01335; Radical_SAM; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 1.10.150.320; Photosystem II 12 kDa extrinsic protein; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR023874; DNA_rSAM_put.
DR   InterPro; IPR007197; rSAM.
DR   InterPro; IPR010994; RuvA_2-like.
DR   NCBIfam; TIGR03916; rSAM_link_UDG; 1.
DR   PANTHER; PTHR21180; ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR21180:SF9; RADICAL SAM DOMAIN PROTEIN; 1.
DR   Pfam; PF12836; HHH_3; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SFLD; SFLDG01102; Uncharacterised_Radical_SAM_Su; 1.
DR   SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR   SUPFAM; SSF47781; RuvA domain 2-like; 1.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199132};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT   DOMAIN          58..233
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000259|Pfam:PF04055"
SQ   SEQUENCE   424 AA;  48848 MW;  6F71371B68431A86 CRC64;
     MEKLRILAES AKYDVSCSSS GTVRRGKKGM VGSTVGGVGI CHSFADDGRC ISLLKVMLTN
     YCMYDCAYCI NRRSNDIRRA TLSVSELEEI TMEFYRRNYI EGLFLSSGVV RNPDYTMERL
     TAIARDLRLV HRFNGYIHLK SIPGASRELL NEAGRYADRM SVNIEIPKEE SLKLLAPEKN
     HQSVFQPMKL IQQGVLENKE DRRRMRHVPR FVPAGQSTQM IVGATKETDK DILTMSSMLY
     GQPTMRRVYY SGYVSVNTYD PRLPVLKQPP LVRENRLYQA DWLLRFYHFT VDEIVDDLHA
     NLDLEVDPKL AWALRHPEAF PVDINTADYE QLLRVPGLGT KSAWLIVNSR RFNRLTSYDL
     KKMGVVMKKA KYFITCHELT STYSTPIVGV NELRPERLRP LLISKTQQKR IAEEQQLKLD
     FDEE
//