ID   A0A1H8B4Y2_9BACT        Unreviewed;      3227 AA.
AC   A0A1H8B4Y2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Amino acid adenylation domain-containing protein {ECO:0000313|EMBL:SEM77971.1};
GN   ORFNames=SAMN04488505_106122 {ECO:0000313|EMBL:SEM77971.1};
OS   Chitinophaga rupis.
OC   Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC   Chitinophaga.
OX   NCBI_TaxID=573321 {ECO:0000313|EMBL:SEM77971.1, ECO:0000313|Proteomes:UP000198984};
RN   [1] {ECO:0000313|EMBL:SEM77971.1, ECO:0000313|Proteomes:UP000198984}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21039 {ECO:0000313|EMBL:SEM77971.1,
RC   ECO:0000313|Proteomes:UP000198984};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC         Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR   EMBL; FOBB01000006; SEM77971.1; -; Genomic_DNA.
DR   STRING; 573321.SAMN04488505_106122; -.
DR   OrthoDB; 4317020at2; -.
DR   Proteomes; UP000198984; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   CDD; cd05930; A_NRPS; 3.
DR   CDD; cd19543; DCL_NRPS; 1.
DR   CDD; cd19531; LCL_NRPS-like; 1.
DR   Gene3D; 3.30.300.30; -; 3.
DR   Gene3D; 3.40.50.980; -; 2.
DR   Gene3D; 1.10.1200.10; ACP-like; 3.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 3.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR   Gene3D; 1.10.10.1830; Non-ribosomal peptide synthase, adenylation domain; 1.
DR   Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 3.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   InterPro; IPR041464; TubC_N.
DR   InterPro; IPR044894; TubC_N_sf.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 3.
DR   PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 3.
DR   Pfam; PF13193; AMP-binding_C; 2.
DR   Pfam; PF00668; Condensation; 3.
DR   Pfam; PF00550; PP-binding; 3.
DR   Pfam; PF18563; TubC_N; 1.
DR   SMART; SM00823; PKS_PP; 2.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 3.
DR   SUPFAM; SSF47336; ACP-like; 3.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 6.
DR   PROSITE; PS00455; AMP_BINDING; 2.
DR   PROSITE; PS50075; CARRIER; 3.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198984}.
FT   DOMAIN          1032..1106
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   DOMAIN          2080..2155
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   DOMAIN          3136..3211
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
SQ   SEQUENCE   3227 AA;  363167 MW;  5E590426870EC4CD CRC64;
     MNISQLLVEL NHHDISVSLD GDDLLIGFEG DEIAETLVNR IRENKSELIA YLKRYAAQGS
     FAEITPVPVQ ESYPMSFSQR RLWILSQYPE MSRAYVIPNH VDMTDDLDIT LFKKAVDAVI
     TRHEILRTVF RENAGGEVRQ WILPLDELGF EITLVDLSEQ EDAVAQAGEY MEEDSFRLFD
     LENGPLFRAS LIKLSDKQYR FFYVMHHIIS DGWSLDVLAK DVFAYYHAYT NNTSPVISPL
     RIQYKDYANW QGLQLTAGKV NDDRNYWLAQ FKDGIPVIEL PSEQTRPAIK TNNGILLETW
     LSKETTQKLR AYTQKQEGSL FITLLSLWNV LLYRYTGQQE MVVGTAVAGR EHAYLEDQIG
     FYVNTLALKN TLAPKETFTD NYTKVKANTL AALSHQTFPF DLLVEELQLM RDSSRSPLFD
     VMLTFQSAGA NPIELNNEMV NGIHYRGRRN AKFDIEINAL EVGAYVQLIV NYNTDVYNPE
     IIRQMMQHFK QLAAVVLDDP DQHIDTCNFL SVPERNELLY AFNDTKADYP SDKTIIELFE
     AQAAQYPDRV AVVAEAGSLT YRQLNEKANQ LGHFLRQHYD MAADDLVGIE LPRGLNLVTA
     IFGVLKAGAA YVPIDPNNPE DRKSYIKKDA ACKCIIDPDF MAGFEPCADQ YPVQNPGKIN
     NAKSLVYVIY TSGSTGHPKG VMIAHHALVN RLVWMQKAYA LGKADVILQK TTYSFDVSVW
     ELLWWGLYGA QVYLLAPEAE KVPSKIVQSI EDGEVTVMHF VPSMLLPFLH YIKQFPEEKA
     KLLSLKQVFT SGEALSKDHS TLFREQLPWV ALMNLYGPTE ASIDVTYYDC AAPRADNIIP
     IGKPIDNTKM YVLDEQLQLV PIGVKGKLYI GGEGLARGYV NNETLTAKKF ITNPFEPGQL
     IYDTGDVAQW LKDGNINFLG RIDDQVKIRG FRIELEEIAY HLREKEDIAA AVVLVRETIT
     GQKELVAFVV SDKEQDVAAL RMHLAAKVPH YMVPAGFVQV DKIPLNASGK TDKRKLLASA
     QPDLSNKIAY SAPVTDQEKI LVQVCEIVLN KERISVKDNF YNLGGDSIKS IQIVSRLKQL
     GYTLKVEAVL QTPVLETLAS QLVVNATEQA VNSTALFFPG LTAESLNAVK ADENITAVYE
     LSPLQQGIYF HWLTSSSPSL YTGQIAYRVQ LNTITLHAIQ EAYQQLINRH AVLRTSFVHH
     LADIPLQLVR RNVTANFHYD SLPAFLEERD VEPYIKQYKL KDRETGFDLA AHSLMRLKVL
     DLGANRYEFV WSHHHILMDG WCMGILIRDF NRLLNGESLP EPKPYLDYIH WLRSINTSLS
     LDHWKQYLED YTSVATIPFL KPQQQEYKEE KRSVTIKGAL FNKLKALCNK LAITQNTFLQ
     AAWGFLLSRY NNTNDVVFGA VVSGRPAELD GIENMVGLFI NTIPVRIKYE EDCTPVKLLT
     ATQQAGISST AHHYLNLAKV QAQSELGANL LNHIVVFQNF PIEQMVKEAA VTTDQLQVET
     VEFVQQTNYD FNLLVFPGEA ALQVDFMFNA GKYDATAITS LAAHLHSIIE QFVTAEDQPL
     SRINFLPAAD RALIFEKFNA TEVAYEPGKT VLDLFRERVQ EQPELTAVAY ENAHLTYREL
     DLVTSRLAGY LQQHYSIQPN DLVGIQLERG LNMLIAILGI LKCGGAYVPV DTEYPAERVK
     YIAADSSYKV CIDAIFMETF QQKEQTPFTE VNIPASTLAY AIYTSGSTGN PKGVLNDHAG
     LYNRLLWMRD DLGINAADII LQKTPYTFDV SVWELVMPAI TGCKLVFAKP GGHKDPLYLQ
     ELIAAEKTTI LHFVPSMLAI FLEGLDADKC KTLKHVVCSG EALPAATVEA FKTQLPWVRI
     HNLYGPTEAA IDVTSIELTK VDTRTCGVTI GKPVANTRIF IVDKHLQPQP VGVPGELLIE
     GVQVARGYIN QRELTEQKFI TSPFNANYRA YRTGDLARWL PNGEIAYMGR IDHQVKIRGN
     RVEPGEIEIC ITGSGYVEHA AVLVRGEGTP HKYLAAYVIP KAGYNQELLY QYLKNQLPEY
     MIPGRVVELE EFPLTSSGKL NRRALPDPGD SDLAATTYEG PRNEIESALA NIWEEVLNLE
     RVGIHDNFFR IGGDSILSIR LISKINKQFN VGLTIGQLYE CSTITGLSEV INNNLGISAA
     RQKLKDETIA RVAQLKEKVL EVIPDAASIE DIYPMSDIQR GMVILSTLNP GSGMYHDQFI
     FQIPAVRPDL FEQAFSKLVW KHPALRTRFD LSTYGEDIQI VDKQIAVNIG YHNIQASATA
     AQEEHIRNYM LQERKRPFNM GEAPMWRADL FSISPETDVF LFQFYHAILD GWSVASLNTE
     LSHIYQQLAD NTQLFHIEKL RSTYRDAILG ELYEKNDPET IHFWKNELAD YKRLDLFKNA
     PVMQSYTGVY PAHFINSLRE RCRQEGISMK TAFYGALVYV FKMLSYEEDF VIGMVTNNRP
     VVEDGDKILG CFLNTIPVRN RLENTHRLSW RAYFKRMEQQ LTGLRTKERM TLYEISKITN
     ERDAGRSPFF DVLFNYVDFH VYNELGAIHT PAAGEVPAQR LNVASFEATN TFLDIDVIAS
     GETIRLIYGL RYLLKIDVPI DTLHTYVNQV LTAFVIQAAE KINDTNLLPA AEQEKILKHF
     SATETRNNAD KTILQLFSES AGKNPDKAAL IEHEQALSYR EMDGCINQLA GYLVNDRNIA
     KGDLVGIEME PGAWTIIAML AVMKAGGVYV PVNPRYPEKH KTFIYEDSKC KIVLNDTLIA
     GFKEIREHYS STFTAVACSL NDLAYIIYTS GSTGNPKGVQ IRHLSLADYA ITFSAYFQLT
     PADSIVQQAS ISFDTSVEEI FPVLISGGTL VLFQGKNDID QLLQLCEDHK ISILSTNPFV
     LQHLNNVYHK YAFNFRVLIS GGDALKPGYI DNIWTTVPVY NTYGPTESTV CATYHKVTAL
     EDSIPIGKPI PNRHIHLLYP GTEQLTPIGA VGEICLSGKG IAAGYLNRPE LSAVKFVPNP
     YLDGATMFCT GDLGRWLPDG SIEFIGRKDD QVKIRGYRIE LGEIETALSG TGLVQDAIVL
     VKGMEEENKR LVAYIIPGAG YTQEKLLGYL AQVLPEHMIP GVIMEMDHFA LTLNGKPDKK
     ALPEPDALQF LQDIEPPRNK TEEKLVHIWC ALLNREQVGV TTSFFQLGGT SLTIIRLRQK
     IEEEIGVSVN IVDLFNHTTI RDFAATISQE RTAGMESSNL TPATLKF
//