ID   A0A1H8B9Q1_9FIRM        Unreviewed;       458 AA.
AC   A0A1H8B9Q1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Alanine or glycine:cation symporter, AGCS family {ECO:0000313|EMBL:SEM79139.1};
GN   ORFNames=SAMN05216180_1773 {ECO:0000313|EMBL:SEM79139.1};
OS   Hydrogenoanaerobacterium saccharovorans.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Hydrogenoanaerobacterium.
OX   NCBI_TaxID=474960 {ECO:0000313|EMBL:SEM79139.1, ECO:0000313|Proteomes:UP000199158};
RN   [1] {ECO:0000313|EMBL:SEM79139.1, ECO:0000313|Proteomes:UP000199158}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.5070 {ECO:0000313|EMBL:SEM79139.1,
RC   ECO:0000313|Proteomes:UP000199158};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
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DR   EMBL; FOCG01000001; SEM79139.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8B9Q1; -.
DR   STRING; 474960.SAMN05216180_1773; -.
DR   OrthoDB; 9804874at2; -.
DR   Proteomes; UP000199158; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF14; SODIUM_AMINO ACID (ALANINE) SYMPORTER-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199158};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        14..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        72..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        99..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        148..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        186..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        217..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        243..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        304..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        356..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        389..407
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        419..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   458 AA;  48840 MW;  0C75E09FF9DD9D9E CRC64;
     MEVISNIVKV VNGFLWDFAL LFLLCGTGIY FTVRLRFVQV RKFKEGMKAV FGNIKLRGDK
     ANEDGMSSFQ SLATAVAAQV GTGNIAGAAT AIASGGPGAI LWMWLSAFFG MATIYSEATL
     AQQFKTRVDG EITGGPVYYI KAKFKGKFGT FLAGFFSVAI ILALGFMGNM VQSNSIGDAF
     KTAFGVNPLI VGIFVAAVAA FIFIGGAKRI ASVTEKIVPI MAVLYVLGSL IVLIFNWRNV
     GNAFVQIFVL AFNPQAMAGG VVGATVQKAL SLGVARGLFS NEAGMGSTPH AHAMAKVKHP
     CEQGVVAMIG VFIDTFIVLT MTALVIITTG ALSSGKTGSA LAQNAFNSVF GSAGNIFIAI
     CMLFFAFSTI IGWYFFGEVN VKYLFGKKAV KFYSLLVVVF VILGSLMKVD LVWSMSDMFN
     ALMVIPNLIG VLALSGLVVK LNKRYENGNL EPLDLDLK
//