ID   A0A1H8BQK2_9FIRM        Unreviewed;       449 AA.
AC   A0A1H8BQK2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Putative gluconeogenesis factor {ECO:0000256|HAMAP-Rule:MF_00973};
GN   ORFNames=SAMN04488698_12031 {ECO:0000313|EMBL:SEM85083.1};
OS   Candidatus Frackibacter sp. WG12.
OC   Bacteria; Bacillota; Clostridia; Halanaerobiales; Halobacteroidaceae;
OC   Frackibacter.
OX   NCBI_TaxID=2017977 {ECO:0000313|EMBL:SEM85083.1, ECO:0000313|Proteomes:UP000199298};
RN   [1] {ECO:0000313|Proteomes:UP000199298}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WG12 {ECO:0000313|Proteomes:UP000199298};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for morphogenesis under gluconeogenic growth
CC       conditions. {ECO:0000256|HAMAP-Rule:MF_00973}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00973}.
CC   -!- SIMILARITY: Belongs to the gluconeogenesis factor family.
CC       {ECO:0000256|HAMAP-Rule:MF_00973}.
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DR   EMBL; FOCA01000020; SEM85083.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8BQK2; -.
DR   OrthoDB; 9783842at2; -.
DR   Proteomes; UP000199298; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043743; F:LPPG:FO 2-phospho-L-lactate transferase activity; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-UniRule.
DR   CDD; cd07187; YvcK_like; 1.
DR   Gene3D; 3.40.50.10680; CofD-like domains; 1.
DR   HAMAP; MF_00973; Gluconeogen_factor; 1.
DR   InterPro; IPR002882; CofD.
DR   InterPro; IPR038136; CofD-like_dom_sf.
DR   InterPro; IPR010119; Gluconeogen_factor.
DR   NCBIfam; TIGR01826; CofD_related; 1.
DR   PANTHER; PTHR30135:SF3; GLUCONEOGENESIS FACTOR-RELATED; 1.
DR   PANTHER; PTHR30135; UNCHARACTERIZED PROTEIN YVCK-RELATED; 1.
DR   Pfam; PF01933; CofD; 1.
DR   SUPFAM; SSF142338; CofD-like; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00973};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        16..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        60..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   449 AA;  49655 MW;  13C5EF0A3647F7B9 CRC64;
     MKIFKWLYPG LKIKRWLFLS IVGILLISVG LTVAIGFEFL TVLENELLAL IYDLTGHFSQ
     VFNVVVGALI IVIGIICVIY GISKMINSII EALLPDNEEE LVELVYQQRH LKRGPKIVVI
     GGGTGLPTML RGIKEFTSNI TAVVTVADDG GSSGVLRDEL DILPPGDIRN CLVALADTEV
     LMESLFQYRF DTGEELNGHS FGNLFIATMT KVIGDFEEAI KESSKVLAIR GRVLPSTLED
     VVLFAETEDG EVIKGESKIP EVNKRIKRVF LEPGDCDSLP EVIKEIEEAD AVVLGPGSLY
     TSVIPNLLVS EISEAIKRTD ALKIYNCNVM TQPGETTGYT AADHIQALYD HGGSEIVDYI
     LVNNEGISAE LLEKYQEEGA EPVEVDFGRL EELGINVVQA PLLNKEDLVR HNPHKLAEVI
     IKLIIKLKQN TEQGPLIDLY LRNKFKKDR
//