ID   A0A1H8C6Q5_9BURK        Unreviewed;       795 AA.
AC   A0A1H8C6Q5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Alpha,alpha-trehalose phosphorylase {ECO:0000313|EMBL:SEM90745.1};
GN   ORFNames=SAMN05216319_4902 {ECO:0000313|EMBL:SEM90745.1};
OS   Duganella sp. CF402.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Oxalobacteraceae; Telluria group; Duganella.
OX   NCBI_TaxID=1855289 {ECO:0000313|EMBL:SEM90745.1, ECO:0000313|Proteomes:UP000198529};
RN   [1] {ECO:0000313|Proteomes:UP000198529}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CF402 {ECO:0000313|Proteomes:UP000198529};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 65 family.
CC       {ECO:0000256|ARBA:ARBA00006768}.
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DR   EMBL; FOBG01000004; SEM90745.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8C6Q5; -.
DR   STRING; 1855289.SAMN05216319_4902; -.
DR   Proteomes; UP000198529; Unassembled WGS sequence.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 1.50.10.10; -; 1.
DR   Gene3D; 2.70.98.40; Glycoside hydrolase, family 65, N-terminal domain; 1.
DR   Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR005194; Glyco_hydro_65_C.
DR   InterPro; IPR005195; Glyco_hydro_65_M.
DR   InterPro; IPR005196; Glyco_hydro_65_N.
DR   InterPro; IPR037018; Glyco_hydro_65_N_sf.
DR   InterPro; IPR017045; Malt_Pase/Glycosyl_Hdrlase.
DR   PANTHER; PTHR11051; GLYCOSYL HYDROLASE-RELATED; 1.
DR   PANTHER; PTHR11051:SF8; PROTEIN-GLUCOSYLGALACTOSYLHYDROXYLYSINE GLUCOSIDASE; 1.
DR   Pfam; PF03633; Glyco_hydro_65C; 1.
DR   Pfam; PF03632; Glyco_hydro_65m; 1.
DR   Pfam; PF03636; Glyco_hydro_65N; 1.
DR   PIRSF; PIRSF036289; Glycosyl_hydrolase_malt_phosph; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE   3: Inferred from homology;
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          36..295
FT                   /note="Glycoside hydrolase family 65 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03636"
FT   DOMAIN          352..712
FT                   /note="Glycoside hydrolase family 65 central catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF03632"
FT   DOMAIN          722..783
FT                   /note="Glycoside hydrolase family 65 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03633"
FT   ACT_SITE        513
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036289-50"
FT   BINDING         385..386
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
FT   BINDING         625..626
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
SQ   SEQUENCE   795 AA;  88845 MW;  B821681DC2D3BFDF CRC64;
     MTQKPVFFKI QTALNRFSKE FAVQQHTYPL DAWCIRETSF DTASHFLDET LFALGNGYIG
     LRGTGEEGYS GPAGTSLDGT YLNGFYESEP IQYPEAAYGL AKVNQFMLNV PNAKGIELWL
     GDEKFDLLAG SIQSYERVLD FRTGVLTRVV EWTSPQGRSV RVRSRRLVSF ENKHLFAIAF
     EVTSLNFEGR LRLVSALDGA VKNLEAGDDP RVGSAISGPT LHMIDSEQAG GFSALVQKTH
     NSGFTLVSAT ESVLSAGLPP VTAQDGQRLT QTWELAVSAG ESVALNKYGS YYSSRDYDTK
     ELMWRSKDTL SNAAAAGFED LRLAQEQYLA DFWQQADVQI AGDDALQQGM HFNQFHLLQS
     VGRDGKTNIS AKGVTGEGYE GHYFWDTEIY IFPFFLYSKP EIARKLLEYR YAGLPKARER
     ARQMSHSVGA LYPWRTIAGD ECSAYFPAGT AQYHINADIA YSIKMYMEAT DDQEYLVKAG
     AEIVMETARI WTGIGSYDRE GRFCINQVTG PDEYTALVNN NYYTNVMAQM HLSFAASIAE
     QLQAQAPSEF ARIAAVMALD AGEPAEWRRA ASLMHLPYDD ALQIHAQDDS FLSKKVWDFA
     NTPKENYPLL LNYHPMVIYR HQVCKQADVV LALLLLSDRF SLEDKRRDFD YYEAVTTHDS
     SLSSCIFGII AAEVGYQDKA YHYFMETARL DLDDTHGNTH YGVHTAAMAG TWLGVAFGFG
     GMRVVGSALH FAPTLPKQWQ HYTFKIHFRG ALLEVHVEPG RVEYRLLQGE SLSFTHGGES
     VALSLSQPKQ SRSFA
//