ID   A0A1H8CZ06_9BACL        Unreviewed;       869 AA.
AC   A0A1H8CZ06;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Mannosylglycerate hydrolase {ECO:0000313|EMBL:SEN00323.1};
GN   ORFNames=SAMN05444955_104202 {ECO:0000313|EMBL:SEN00323.1};
OS   Lihuaxuella thermophila.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
OC   Lihuaxuella.
OX   NCBI_TaxID=1173111 {ECO:0000313|EMBL:SEN00323.1, ECO:0000313|Proteomes:UP000199695};
RN   [1] {ECO:0000313|EMBL:SEN00323.1, ECO:0000313|Proteomes:UP000199695}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 46701 {ECO:0000313|EMBL:SEN00323.1,
RC   ECO:0000313|Proteomes:UP000199695};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
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DR   EMBL; FOCQ01000004; SEN00323.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8CZ06; -.
DR   STRING; 1173111.SAMN05444955_104202; -.
DR   OrthoDB; 9764050at2; -.
DR   Proteomes; UP000199695; Unassembled WGS sequence.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   CDD; cd10815; GH38N_AMII_EcMngB_like; 1.
DR   Gene3D; 2.60.40.2220; -; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR041147; GH38_C.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF2; MANNOSYLGLYCERATE HYDROLASE; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF17677; Glyco_hydro38C2; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000313|EMBL:SEN00323.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199695}.
FT   DOMAIN          275..353
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
SQ   SEQUENCE   869 AA;  100624 MW;  06A8DC91CDB18AA6 CRC64;
     MKKVHIVPHM HWDREWYFST EESRILLVNN MEEIMEMLEN NPDYPHYVLD GQTAVLEDYF
     AAKPENRERV KKLVQEGKLI IGPWYTQTDE MIVGGESIVR NLLYGIKDCK ELGSHMQIGY
     LPDSFGQSSQ MPQILNGFDI KYSIFWRGAS ERHGTDKTEF YWESGEGSKV LVQLFPLGYA
     IGKYLPEDEE KLKERIDKYF AVLDRGATTD HIILPNGHDQ MPIQKNIFAI IEKLKKLYPD
     REFFLSKYEN VFEELEKNRN LPTLEGEFLD GKYMRVHRSI YSTRMDIKAS NTRIENKITN
     ILEPLASLAY SLGFEYHHGL IELIWKEVLK NHAHDSIACC CSDQVHQEIY NRFCLAEEKV
     DQLIRFYKRK IVDSIDTEWN VDRLTAFNLL PYDREEVMTT TVITKLESFK LLDEEANELE
     FEVLHSEMID PGLIDRQIVH YGNYDPFIKY TIQFKDCLPP LGYKTYFVVE SNGKMNHSTV
     HKDQVETDFY EITVNPNGTL NIFDKQLMKT FRNVLLLENG GDDGDEYDFS PLPEEQLIYS
     DQVEADVDIK QNQYAATIDI RCTLKVPGDI NKRKEGVADS SVDIHLTLTI PNHKPIIEVN
     VEIDNHAKDH RLRALIPTGI ASQFSVSDNQ FGFMKRDVYD SALDIWEKEG WDERPDPIYP
     MLNFVGLSNE KFGVSVLTNS TREFEIVGDE YDTIAVTLFR SVGVLGKEDL LRRPGRPSGI
     KLPTPDSQML RRITLQFAIT THAKSTLQAN VARMAKEYLT PIHFYNKIPF DAMKMNKADV
     KTPARYSFLK EVQPEVVMST LKKAENSDQF VLRFFNPTDE EKTASFQLTT SGRQVYTANL
     NEKPLEVLKA EDGQFQLKVQ RNQVKTILF
//