ID A0A1H8DB06_STIAU Unreviewed; 3978 AA.
AC A0A1H8DB06;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Acyl transferase domain-containing protein {ECO:0000313|EMBL:SEN04551.1};
GN ORFNames=SAMN05444354_12918 {ECO:0000313|EMBL:SEN04551.1};
OS Stigmatella aurantiaca.
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Archangiaceae; Stigmatella.
OX NCBI_TaxID=41 {ECO:0000313|EMBL:SEN04551.1, ECO:0000313|Proteomes:UP000182719};
RN [1] {ECO:0000313|Proteomes:UP000182719}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17044 {ECO:0000313|Proteomes:UP000182719};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOAP01000029; SEN04551.1; -; Genomic_DNA.
DR Proteomes; UP000182719; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd08955; KR_2_FAS_SDR_x; 2.
DR CDD; cd00833; PKS; 2.
DR Gene3D; 3.30.70.3290; -; 2.
DR Gene3D; 3.40.47.10; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 3.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 3.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 2.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR020807; PKS_DH.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR049552; PKS_DH_N.
DR InterPro; IPR013968; PKS_KR.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 3.
DR Pfam; PF16197; KAsynt_C_assoc; 2.
DR Pfam; PF00109; ketoacyl-synt; 2.
DR Pfam; PF02801; Ketoacyl-synt_C; 2.
DR Pfam; PF08659; KR; 2.
DR Pfam; PF21089; PKS_DH_N; 2.
DR Pfam; PF00550; PP-binding; 3.
DR Pfam; PF14765; PS-DH; 2.
DR SMART; SM00827; PKS_AT; 3.
DR SMART; SM00826; PKS_DH; 2.
DR SMART; SM00822; PKS_KR; 2.
DR SMART; SM00825; PKS_KS; 2.
DR SMART; SM00823; PKS_PP; 3.
DR SMART; SM01294; PKS_PP_betabranch; 1.
DR SUPFAM; SSF47336; ACP-like; 3.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 3.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 4.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 3.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS50075; CARRIER; 3.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 2.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000182719};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SEN04551.1}.
FT DOMAIN 1..65
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 83..507
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 2094..2169
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2194..2622
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 3882..3959
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1423..1442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3978 AA; 423519 MW; 0613A1EBC9545C12 CRC64;
MASQVGIEAR AVGTAEPFFA LGMGSVFATK LIAELARWLD RPLSPTLVWE HPTIDKLARH
LSGADAPKVD LQAQKLEAGV DEAEPIAIVG LACRFPNAPD AGAFWRVLQE GRDCVTEVPG
DRWDASLYYD PEPGTPGKIV TRYGAFLDSV DRFDPTFFGI SPREAGQLDP QQRLMLELSW
EALEDAGIAP QRLRGSRTGV FTGMVWRDYA DLQTIHNAAP TLHTCTGHAG GILANRISYA
LGLEGPSLAI DTACSSSLVA IHEACRSLRS GESAIALAGG VQLNLSPRTF MAVSAFGALA
PDGRCRTFDA RASGYVRGEG GGVLVLKPLS RALADGDTLY CVIRGSAVNN DGASNGLTAP
NPKAQERLLR DAYAAAGIDP AQVQYVELHG TGTPLGDPIE AGALGTVLGS AREVERPLHV
GSVKTNIGHL EAAAGIAGVI KVALSIRHQQ LPASLHFEQP NPRIAFDDLR LRVQTQLGSW
PVADAPAVAG ISAFGFGGTN CHIVVEEHRA GRRPSTVPVS PPQTQPAAAP KTAFLFAGAG
SSWWGMGREL LGTEPVFRSR FEECDAAFRP LGGWSLVETL LSSQARSRFG KGEIQLPLVL
AFQISLAALW RSWGIEPSAT LGYSVGEWSA AQVAGILTIE EVFALAHHYI QVQKGVAGGV
GMAVVGLSGA EAAERIAPYG GRISIASENG PHSTGLGGEA AALRDFTASM TAEGVFARLV
EIDFYAHIPE VEPLKQLFLQ TCPALRPLPG RIPMVSTVSG TFVEGNTLGP AYWADNFREP
VRFASAVKTL LDSGHDVFLD VNPHPIHEHS VLENFRAGTT RAAFIASMRR GEPSLQGLHR
ALTQLSDSGS PVRWDRILPG MATGASSPAK AELFVASART EQALREHAER IAGQLRRDAS
ASLTDLCYTA GVRRSHHEHR LALVAETRAA LEEGLSAFAR GEIRQNPSQG VVRASEAPRI
GFVFSGQGSF PLGSSVQLFE EEPRFREAFE RCEQVFRSQT GASLIEALKA ERENPHPPRT
ETEQPLLFAF QVALAALWES WGIRPAAVVG HSVGEISAAH IAGVLSLEEA VSLVVSRSRL
MGRAAGQGGM ATVEAPLAKV EPLLAEYGAE LAIAAVNGPG NVVVSGGLAA LNALRDQLTG
QGVRVRLLNV NYAFHSAQMA PYLGDLDAVL RELKPQSPRI PLYSTVRGSL ASSSDFGADH
WRANVRERVL FAPAVEAMLA DGHGIFVEIA PHPVLLQPLS RILEASPSKD AVAVFSTRRD
RAPRSALLGS LGTLYTLGHE PSWKGVFPDG GRAVELPSYP WQRQRYWFDA APGSAPEPVH
PLLGRRVEAP SGQYAFQSTF RSDRLQLLSD HRLYGTVVVA GASMLGMMLV AARQIWGEAR
CVLQDVLFLQ PLVLGDTEER TVQVSIAADG AFRILSRAGQ ESEGASSWTE HATGRLERGA
ADEAEAEREQ LSALEARFQP LASAGSFYEG IARQGLDLGR QFRWLEALWQ GEREALGRLR
AAEPADGAGD YRFHPGLIDS CFQVLGAVAG FTSIEGLAFV PIGVGRFAVR GEPRPPRFCH
LVLRSGSGKV NEASSVDLRL LDESGLAVAE VSGLVIRRAP REVMLRREVT APSLVLRTEW
QPQSVPAVSP AAPAAWVLLA DRGGLASRLA EQLTSRGGRV EVLAPGEGAN SLPGCLDAFD
AAGTACTGIV DLRGLDAGPS LDAVQGALRL VQQVIARRTP AAPRLVLVTR GTQVTGSNDG
PIAFEQAPLW GLGHVIALEH PELSCQRIDL DPSDTTAAGA QLAAELAAPG REDRVAFRAG
RRLVSRLART KLPPAVRPLP LTGEATYLIT GGLGGIGLEL ARWMVERGAR HLVLMGRSAP
GARAQEALEA LRGAGAKIVV ALGDVAEREP LARVLGEARA SMPPLRGVLH AAGVLDDGLL
VRQSEERIAR VLAPKILGAM NLHRETLEDR LDFFVLFSSV SSVFGTSGQA GYASANAFLD
ALAHHRRAQG LTALSVNWGP WADVGMAARL PPEAGKAWSS FGLGLLTPSA GLAALERLLC
SETAQVVVAG ASEAEVKGDF APFFEVLSSK KPEAARPASV GGTLAGASPR EYRTRLRALL
QAQAATVLGV PPSVPVDPRR PLQELGLDSL MALQFRNSLA ASLGRSLPAT LLFDHPTIEK
LFEFLTRDLA PVEEAASAPS RRPVKPAVAS NGAAEPIAVV GMSCRLPGSV KNPDDFWRLL
AHGVNAVREV PKDRWSLDTW YDPDPEAPGK MYSRHGGFLD EVDPFDASFF GISAPEARSM
DPQQRILLEL GWEALESAGL AVDQLKGSPT GVFLGICLSD YALLELNSPD PTGINAYSGS
GGVLSVAAGR IAYALGLEGP TLAVDTACSS SLVAAHLACQ SLRNGECNLA LVGGSNLLLS
PRMSVYFSKL KALAPDGACK AFDSSANGYV RGEGAGVLVL KRLSDAIADG DPILSVIRGT
AVNQDGRSNG LTAPSRAAQE RVIESALRQG GVSPLDVSYV EAHGTGTSLG DPIEVQALAA
VLGKDRPRSM PLGIGSVKTN IGHLEGAAGV TGLIKAILAL RHRELPRSLH FKNPSPHIPW
EELPVEVIAE HRPWTVPEGK RRILGVSSFG FSGTNAHVIL EEAPAETRSE APGTGERPEL
LVLSARAPQA LQEVAMRFSA QLSGRAGDSA APLHDVCYSA NCRRSHHEHR LAVVARSRSE
AASAIDAFLS GLAHPDAQSG YALPGAVPRV VFLFTGQGGQ WPGTGRALLE EEPVFRSALQ
AADEVLKGLA GWSVIEELQR ETPRFDQAAI SQPAHFALQS ALLALLRSWG IEPDAVAGSS
IGEVAAAYAA GVLSLEEAMR ITVARSRILH AVAGKGAMAL VELSEDEATE AVAGYAQRLS
VAAINSQKST LLSGEAAAME ELLNALTARG VSSRRIGLDY ASHSPAVEPY IDDLKQALQG
LRPRSATLPI YSTVTGRLAE DGDFDSGYWA RNLRQPVRLA PVLTTLATEG YTLFVELGPN
AVMARPVQQC FQAAGKSAVV LSTLRRGEPE RHTLRSLLGG LFVAGITPTW NRLFSEGGTL
VPLPSYPWQK ERYWISNAAS AARPQISAPG QGALHGRRVR SPLAESLFET DLSVEKMPFL
REHLLHDALV VAGAAHVALA ISALRELRGT SPVRLADIVF PRPLVLKEGS ENPVSVVVGR
EQGGRAPLRI QSPQGNEAEW LTHAEGWVLP ASSRLEEPAQ VPLAELRARC PNGLDVSPVY
RAMGAEGIGL GRRFQWVEQL WQGDGEALGR MRAAESADQH PSAPLHPGLI DSIFHVLRAV
PGIGRGDGVP YIPIGIEGMC FLTPPQGSLW AHVKLRPEGG RDGETLSADF RLFEESGKTV
AWIDGLIVKR APREAFQRQE GRDLDDKLFQ VRWQPVPMAA AVPGNGPWLL VAGQEALGAE
LATRLKAQGK VCQVLAAPAQ AESGEAFVRR LEEALASDAY QGVVYLPAFG AEPKSPEGTS
QAALEGLSGA VQVLQSLAKT ERGTPPRLWL VTRGAQGVEE SPRPLELAQS PLWGLGLAIR
DEHPELRCTL VDLDPDPAVE AAECLLRELL NPDSEDRLAW RGGARLAQRL SALEVVPEPG
AAPVSPEGTY LITGGLGGIG LRCARWLVDA GARHLALLGR SAPSAEVRAV LGALEAEGVT
VRVLQADVAV QEELSKALAA LRADMPPLRG VLHAAGLLDD ALLVRQDRGR LQRVLRPKVT
GALNLDLETR GDPLDFFVLF SSIAAMVGGE GQANYSAANA FLDALAFERR AQGLPAHSLA
WGPWAEVGMV AARSERSAHL AASGIETLAP DEGVAILGRL LRGSAAHVGI FRIDWARWQQ
NRSEKAVPLL AGMLKQQAAS PVPDASEGVP DLQALIRATP EERRKQAEAF LRREVTRILD
LPRPLADGRL PLVRFGFDSL MSLKLKARLE ATLGLSISAA KLLSGLSLDK LVDLVLERIE
TLQPAPVSTD DQMEDFRF
//
