ID A0A1H8DC24_9MICO Unreviewed; 1035 AA.
AC A0A1H8DC24;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Bifunctional [glutamine synthetase] adenylyltransferase/[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase {ECO:0000313|EMBL:TFB91966.1};
DE EC=2.7.7.42 {ECO:0000313|EMBL:TFB91966.1};
DE EC=2.7.7.89 {ECO:0000313|EMBL:TFB91966.1};
GN ORFNames=E3O10_06320 {ECO:0000313|EMBL:TFB91966.1};
OS Cryobacterium luteum.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Cryobacterium.
OX NCBI_TaxID=1424661 {ECO:0000313|EMBL:TFB91966.1, ECO:0000313|Proteomes:UP000297654};
RN [1] {ECO:0000313|EMBL:TFB91966.1, ECO:0000313|Proteomes:UP000297654}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hh15 {ECO:0000313|EMBL:TFB91966.1,
RC ECO:0000313|Proteomes:UP000297654};
RA Liu Q., Xin Y.-H.;
RT "Genomics of glacier-inhabiting Cryobacterium strains.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TFB91966.1}.
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DR EMBL; SOFF01000020; TFB91966.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H8DC24; -.
DR STRING; 1424661.SAMN05216281_103221; -.
DR OrthoDB; 9759366at2; -.
DR Proteomes; UP000297654; Unassembled WGS sequence.
DR GO; GO:0008882; F:[glutamate-ammonia-ligase] adenylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0047388; F:[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR CDD; cd05401; NT_GlnE_GlnD_like; 2.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 2.
DR Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 2.
DR InterPro; IPR023057; GlnE.
DR InterPro; IPR005190; GlnE_rpt_dom.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR013546; PII_UdlTrfase/GS_AdlTrfase.
DR PANTHER; PTHR30621:SF0; BIFUNCTIONAL GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE_ADENYLYL-REMOVING ENZYME; 1.
DR PANTHER; PTHR30621; GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE; 1.
DR Pfam; PF08335; GlnD_UR_UTase; 2.
DR Pfam; PF03710; GlnE; 2.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 2.
DR SUPFAM; SSF81593; Nucleotidyltransferase substrate binding subunit/domain; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:TFB91966.1}; Transferase {ECO:0000313|EMBL:TFB91966.1}.
FT DOMAIN 93..344
FT /note="Glutamate-ammonia ligase adenylyltransferase
FT repeated"
FT /evidence="ECO:0000259|Pfam:PF03710"
FT DOMAIN 380..507
FT /note="PII-uridylyltransferase/Glutamine-synthetase
FT adenylyltransferase"
FT /evidence="ECO:0000259|Pfam:PF08335"
FT DOMAIN 612..859
FT /note="Glutamate-ammonia ligase adenylyltransferase
FT repeated"
FT /evidence="ECO:0000259|Pfam:PF03710"
FT DOMAIN 884..1023
FT /note="PII-uridylyltransferase/Glutamine-synthetase
FT adenylyltransferase"
FT /evidence="ECO:0000259|Pfam:PF08335"
SQ SEQUENCE 1035 AA; 111996 MW; 5A40DB2884EFF11B CRC64;
MERLQLTLTE LVRVGFVDLA EVHARLDEVA ELGANSPHSG SAATGRSTDT RALLPLLTAT
ASPDAALVAL VALLRQGSAE LFALLHTPAA TGRLLKVLGA SSGLADFFLR HPEELPVLTT
PLVVLPSVND LVHDLLDAVG AVAGFSLLID DEAWVALRVR YRRRLAQLAA FDLEQVDPVA
GLDGVARTLS DLATAALETA LAVARTMSSG ETAGRGVFLI DQVRATRLAV IGMGKAGASE
LNYVSDVDVI FVADGDETAG LESSRAVEIA TRLAVLIMRG LGESGIEPEL WEVDPNLRPE
GKSGALVRSI ESHLAYYDRW AKSWEFQALL KARTLAGDRE LGARYIDAVS PKVWSSASRE
NFVESVQRMR ERVTDNIPDE EVDVQLKLGP GGLRDIEFTV QLLQLVHGQT DADVRQAGTL
PALTALATAG YVGRAEATEF ALDYRMLRLM EHRLQLQKLR RTHLVPRDET QLRVLARSTG
LATSAAGLTI RWSETKQRVR GLHERLFYRP LLSAVASLPA EGLNLTSAQA EARLAAIGFL
NTKGALAHIA ALSGGVSRRA AIQRHLLPVL LQWLSQGADP DYGFLAFRRL SDNLGSTYWF
LRMLRDSSGA AERLTRVLSG SRYIGELLEK IPEAVAWLED EADLQPRPLK ALQDEARAVL
GRHESPDAAA TILRAARRRE MLRLAFAALL GQIDLDQLGQ GLTDVNATYI QGVIAAIRGG
DLTVSEDTDA VGGAADPAGT AGDGIEFGVI GMGRFGGAEL GFGSDADVMY VFRAGTLEGE
AANERARFIV RELNRLTEDG RLPLDLDIGL RPEGSNGPAV RSLDSYQAYY RRWSLTWEAQ
ALLRGRGVAG DAALLRDFEA VADEVRYPAA ISEQAVREVR RIKARVENER LPQAADPNRH
LKLGRGSLSD VEWLVQLLQL QHAAAIPALR TTSTLSALAE AVSAGLIPAV DAVVLRSAWI
FASRARSAIT LWTNHTSNVL PTDRAALEGI ARVMEYPPGS GNQLEDDYLA VTRRSRAVFE
RLFYGPVERP GPTVG
//
