ID A0A1H8E6J9_9BACL Unreviewed; 419 AA.
AC A0A1H8E6J9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Nucleoside transporter {ECO:0000313|EMBL:SEN15179.1};
GN ORFNames=SAMN05444955_106161 {ECO:0000313|EMBL:SEN15179.1};
OS Lihuaxuella thermophila.
OC Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
OC Lihuaxuella.
OX NCBI_TaxID=1173111 {ECO:0000313|EMBL:SEN15179.1, ECO:0000313|Proteomes:UP000199695};
RN [1] {ECO:0000313|EMBL:SEN15179.1, ECO:0000313|Proteomes:UP000199695}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 46701 {ECO:0000313|EMBL:SEN15179.1,
RC ECO:0000313|Proteomes:UP000199695};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOCQ01000006; SEN15179.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H8E6J9; -.
DR STRING; 1173111.SAMN05444955_106161; -.
DR OrthoDB; 9783013at2; -.
DR Proteomes; UP000199695; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004740; Nuc_H_symport.
DR PANTHER; PTHR23522; BLL5896 PROTEIN; 1.
DR PANTHER; PTHR23522:SF4; NUCLEOSIDE PERMEASE NUPG-RELATED; 1.
DR Pfam; PF03825; Nuc_H_symport; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199695};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 162..419
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 419 AA; 46148 MW; D5E71EEA2F289019 CRC64;
MQGHSRVVTR LSTMMFLQFF VWGAWYATMG LVLTKHGLSS IIGTAYSVGS IAAIIAPFFL
GMVVDRFFAS ERVLGLLHIV GGILLAIIPA QIHSGNETAL LWMLFIYTLC YMPTLALSNN
VAFHHIEDGA KNFPLIRVFG TIGWIVAGVI IGQLGYSDNP VIFQIAAVAS ILLGLFSFTL
PHTPAPAKGK PLSVRDLLCL DALEMLKERN YLVFMICSML ICIPLSAYYS FTSPFLAAVG
FQNVGGVMTI GQMSEIIFML LVPLFFRRLG VKYMLLVGMI AWTLRYVLFG FGAPAEITAF
MYLGIALHGI CYDFFFVTGF IYAEKKAGEK VKGQAQSLLV LFTQGIGMYI GAMIAGQLFN
QTVTSQGTAA LSEWKVFWLY PALGAAAIAL FFFFLFKDQV GKEHSVPVKQ SPEKKEMEL
//
