ID   A0A1H8EMI8_9SPHN        Unreviewed;       458 AA.
AC   A0A1H8EMI8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Leucyl aminopeptidase {ECO:0000313|EMBL:SEN20695.1};
GN   ORFNames=SAMN05192583_2235 {ECO:0000313|EMBL:SEN20695.1};
OS   Sphingomonas gellani.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=1166340 {ECO:0000313|EMBL:SEN20695.1, ECO:0000313|Proteomes:UP000199206};
RN   [1] {ECO:0000313|Proteomes:UP000199206}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S6-262 {ECO:0000313|Proteomes:UP000199206};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M17 family.
CC       {ECO:0000256|ARBA:ARBA00009528}.
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DR   EMBL; FOCF01000005; SEN20695.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8EMI8; -.
DR   STRING; 1166340.SAMN05192583_2235; -.
DR   OrthoDB; 9809354at2; -.
DR   Proteomes; UP000199206; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00433; Peptidase_M17; 1.
DR   Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR011356; Leucine_aapep/pepB.
DR   InterPro; IPR043472; Macro_dom-like.
DR   InterPro; IPR000819; Peptidase_M17_C.
DR   InterPro; IPR048816; Peptidase_M17_N_1.
DR   PANTHER; PTHR11963:SF53; AMINOPEPTIDASE; 1.
DR   PANTHER; PTHR11963; LEUCINE AMINOPEPTIDASE-RELATED; 1.
DR   Pfam; PF00883; Peptidase_M17; 1.
DR   Pfam; PF21337; Peptidase_M17_N_1; 1.
DR   PRINTS; PR00481; LAMNOPPTDASE.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR   PROSITE; PS00631; CYTOSOL_AP; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW   ECO:0000313|EMBL:SEN20695.1}; Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199206}.
FT   DOMAIN          306..313
FT                   /note="Cytosol aminopeptidase"
FT                   /evidence="ECO:0000259|PROSITE:PS00631"
SQ   SEQUENCE   458 AA;  48530 MW;  AA84E63B61E28578 CRC64;
     MADILLHPDR GQAAHSITVV HPDDWTGWLG NQSPRTRTAV AAHQLTGKAG DRVILPGNGV
     EDWSALLVCD EDASSPWKIA SMPGFLPPGL YRLANGEPGA AMLGWVLGQY RFDRYTKPAD
     QGARVLLTGE PGRIDETLRL AAATAQVRDL VNTGASDLGP AELEAEAEAL ARRFGATLRV
     TQGDALATGY PMIHAVGRAA SRDRQPRLVE LEWGDAAHPR VAIVGKGVCF DSGGLDIKPA
     SGMRLMKKDM GGAAHALALA GLVMAAGLKL RLHLLIPAVE NAIAGNAFRP GDVLSTRAGL
     TVENTNTDAE GRLILGDALC RAGEDKPELI LDFATLTGAA RVALGPDLPP LFTDNEALAS
     ELLSAGERLG DPMWRMPLWN GYDSLLKSDV ADMVNAPDGG FAGAITAALF LRRFVPKGTA
     WAHLDVFAWR PTAKPGRPKG GDAYALRAAF QVLSDRYA
//