ID   A0A1H8G9D4_9ACTN        Unreviewed;       312 AA.
AC   A0A1H8G9D4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=Aminomethyltransferase folate-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=SAMN05660976_07461 {ECO:0000313|EMBL:SEN40137.1};
OS   Nonomuraea pusilla.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Nonomuraea.
OX   NCBI_TaxID=46177 {ECO:0000313|EMBL:SEN40137.1, ECO:0000313|Proteomes:UP000198953};
RN   [1] {ECO:0000313|EMBL:SEN40137.1, ECO:0000313|Proteomes:UP000198953}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43357 {ECO:0000313|EMBL:SEN40137.1,
RC   ECO:0000313|Proteomes:UP000198953};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOBF01000026; SEN40137.1; -; Genomic_DNA.
DR   RefSeq; WP_055504971.1; NZ_FOBF01000026.1.
DR   AlphaFoldDB; A0A1H8G9D4; -.
DR   STRING; 46177.SAMN05660976_07461; -.
DR   OrthoDB; 9796287at2; -.
DR   Proteomes; UP000198953; Unassembled WGS sequence.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   InterPro; IPR045179; YgfZ/GcvT.
DR   InterPro; IPR017703; YgfZ/GcvT_CS.
DR   NCBIfam; TIGR03317; ygfZ_signature; 1.
DR   PANTHER; PTHR22602:SF0; TRANSFERASE CAF17, MITOCHONDRIAL-RELATED; 1.
DR   PANTHER; PTHR22602; UNCHARACTERIZED; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   PIRSF; PIRSF006487; GcvT; 2.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   4: Predicted;
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198953};
KW   Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT   DOMAIN          20..136
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          222..282
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   312 AA;  33892 MW;  F5D4FBA787F3F1B2 CRC64;
     MRSPLLDLPG AVPAEGPDSD VAAHYGDIFA EQRALAKGEA VVDRSNREVI RISGADRLKW
     LNDLTSQKLD TLTPGQWTQT LDLDLQGRVQ HHLTLVDDGE SVLAHVEPGT GQSLIDYLDR
     MRFMLRVEVS RADDLAVLST ATEDFLVPRA ELPGHLGRPL AGLWAYEALR IEAYRPRLGF
     ETDHKTIPHE VGWVGSAVHL SKGCYRGQET VARVHNLGHP PRRLVFLHLD GSVETLPPHG
     APVLLDGQEV GVVGSSARHH ELGPIALAVV KRAVPVDATL LAGGVAASQE VVVPPDAGRN
     VSIDPALRRR IR
//