ID   A0A1H8GVH2_9RHOB        Unreviewed;       634 AA.
AC   A0A1H8GVH2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC {ECO:0000313|EMBL:SEN47714.1};
GN   ORFNames=SAMN04488003_1189 {ECO:0000313|EMBL:SEN47714.1};
OS   Loktanella fryxellensis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Loktanella.
OX   NCBI_TaxID=245187 {ECO:0000313|EMBL:SEN47714.1, ECO:0000313|Proteomes:UP000199585};
RN   [1] {ECO:0000313|EMBL:SEN47714.1, ECO:0000313|Proteomes:UP000199585}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16213 {ECO:0000313|EMBL:SEN47714.1,
RC   ECO:0000313|Proteomes:UP000199585};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
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DR   EMBL; FOCI01000018; SEN47714.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8GVH2; -.
DR   STRING; 245187.SAMN04488003_1189; -.
DR   OrthoDB; 9803111at2; -.
DR   Proteomes; UP000199585; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF13727; CoA_binding_3; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SMART; SM00822; PKS_KR; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199585};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        15..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        50..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        84..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        114..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          287..584
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   634 AA;  67231 MW;  BE80FB795EA1A5FC CRC64;
     MYRTISALSR RAKRVVLLAV DVVLIPAALL GAIALQGLPA DGAGLGATIV GHWLALPLLM
     AIGGLLSSVL GLPLIQLKSY ESHAVALTGL HAVLLGLAAA VLDDMAGFGT PLASFINFAI
     VYFLLAVAAR MGMLQLLLGI YRRGQDQTRV LIYGAGATGR QLAAALRTDE RIFPVAFVDD
     NVATQGTIVQ GLTVYGPMAV EDLIRSHHID RVLLAMPSAS RPQQAQLSRR LEDLGVEVQA
     VPSFAQLTGR VPLLDQLQPV VPGRFLGREA LDAALPDGGT TYAGRVILIT GAGGSIGSEL
     CRQLLGRNPA KLVLCEISEL ALYTIDMELR ALLRRQQTDI VPVLGSITDA GLMARIMADH
     GVQVVLHAAA YKHVPLVESN PVVGMSNNVL GTQVLAQAAA NARVERFILI SSDKAVRPQN
     MMGASKRMAE LVVQDLASRS AVTATGRRSV FTMVRFGNVM GSSGSVIPLF QDQIAKGGPV
     TLTHREVTRY FMTIPEAAKL VLVAGSFASG GDVFVLDMGE PMPIYDLARQ MIAAAGYSVR
     DAADPDGDIE IRITGLRPGE KIHEELLIGE GQLTTPHPKI LQANEAALSE LEMASAIKAL
     RRAIETADEV ALRAVVARWV EGGAHFAQGV EGQS
//