ID A0A1H8ICG5_9ACTN Unreviewed; 292 AA.
AC A0A1H8ICG5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Transcriptional regulator, HxlR family {ECO:0000313|EMBL:SEN66144.1};
GN ORFNames=SAMN05216267_10087 {ECO:0000313|EMBL:SEN66144.1};
OS Actinacidiphila rubida.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Actinacidiphila.
OX NCBI_TaxID=310780 {ECO:0000313|EMBL:SEN66144.1, ECO:0000313|Proteomes:UP000181951};
RN [1] {ECO:0000313|EMBL:SEN66144.1, ECO:0000313|Proteomes:UP000181951}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.2026 {ECO:0000313|EMBL:SEN66144.1,
RC ECO:0000313|Proteomes:UP000181951};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FODD01000008; SEN66144.1; -; Genomic_DNA.
DR RefSeq; WP_075016638.1; NZ_FODD01000008.1.
DR AlphaFoldDB; A0A1H8ICG5; -.
DR STRING; 310780.SAMN05216267_10087; -.
DR OrthoDB; 9792527at2; -.
DR Proteomes; UP000181951; Unassembled WGS sequence.
DR GO; GO:0016209; F:antioxidant activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd03017; PRX_BCP; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000866; AhpC/TSA.
DR InterPro; IPR002577; HTH_HxlR.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR33204; TRANSCRIPTIONAL REGULATOR, MARR FAMILY; 1.
DR PANTHER; PTHR33204:SF26; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00578; AhpC-TSA; 1.
DR Pfam; PF01638; HxlR; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51118; HTH_HXLR; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000181951};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 12..109
FT /note="HTH hxlR-type"
FT /evidence="ECO:0000259|PROSITE:PS51118"
FT DOMAIN 127..289
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
SQ SEQUENCE 292 AA; 30904 MW; E8180C5B93DCFD1A CRC64;
MTHGSGRADP HCAIAAALDV VGDTWTLLIV RDIARGVRRF DGLRAELGVS RKVLAERLKA
LVADGVLTRE PYQERPVRHE YLLTPRGRAL LPVLVGLQDW GDGWVLGDGT TTATAGPGSE
EAARVRELTG TRLPGLRLPG AAGLVDPVSD RQPFTVLYCF PGAYARPESY PPGWSAIPGA
PGCTLESCTF RDRLAEFTAA SAAVVGVSTQ RPDEQAEFAA KERLGFPLLS DDGAALSAAL
RLPVFRTGGA VRLKRLTLVL DADRTVRAAL YPVTDIAASV GAALTAVRDA AS
//
