ID   A0A1H8IXE9_9ACTN        Unreviewed;       709 AA.
AC   A0A1H8IXE9;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Dipeptidyl-peptidase-4 {ECO:0000313|EMBL:SEN73263.1};
GN   ORFNames=SAMN05216267_100939 {ECO:0000313|EMBL:SEN73263.1};
OS   Actinacidiphila rubida.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Actinacidiphila.
OX   NCBI_TaxID=310780 {ECO:0000313|EMBL:SEN73263.1, ECO:0000313|Proteomes:UP000181951};
RN   [1] {ECO:0000313|EMBL:SEN73263.1, ECO:0000313|Proteomes:UP000181951}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.2026 {ECO:0000313|EMBL:SEN73263.1,
RC   ECO:0000313|Proteomes:UP000181951};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FODD01000009; SEN73263.1; -; Genomic_DNA.
DR   RefSeq; WP_069463840.1; NZ_MDCQ01000325.1.
DR   AlphaFoldDB; A0A1H8IXE9; -.
DR   STRING; 310780.SAMN05216267_100939; -.
DR   OrthoDB; 9812921at2; -.
DR   Proteomes; UP000181951; Unassembled WGS sequence.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR001375; Peptidase_S9.
DR   InterPro; IPR002469; Peptidase_S9B_N.
DR   PANTHER; PTHR11731:SF193; DIPEPTIDYL PEPTIDASE 9; 1.
DR   PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR   Pfam; PF00930; DPPIV_N; 1.
DR   Pfam; PF00326; Peptidase_S9; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000181951}.
FT   DOMAIN          133..390
FT                   /note="Dipeptidylpeptidase IV N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00930"
FT   DOMAIN          504..702
FT                   /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00326"
SQ   SEQUENCE   709 AA;  76172 MW;  BB67C1B103E85716 CRC64;
     MDMITSADAP SSSPAAAAYP AQVARTQRYS LGVPGAFTLS ADGSAVLFLR TRGPEDRVSC
     LWLFDGDRER LLVDPAALAA GTGEVPEAER VRRERARERA RGIVAYDASP DLDTVVFALD
     GALWCLEPAR DGSPRPVPTA GPVTEPRLAP RGRGVAYVSG GALHVADLDG GPGRELAVPE
     RADVRYGLAE HVAAESMGRH RGYWWAPDGQ RLLVARVDEA RVQRWWIADA ANPSRPPRET
     AYPAAGTTNA DVSLAVFGLD GTRTEVVWDR AAFEYLATAG WDAHGPLLSV QSRDQRTVQV
     LAADPGTGAT RLLHERTDPA WVQLVPGTPA RTASGALVHT IDDGGTRRLT VDGRPVTPEG
     LQIQSVEQVA GESVLFTAVD EPTESHLWSY TPQEAPLRLS PEPGLHTGQR AAGTLLLASR
     TDDGPRFRLL SGEGAPRPIA CLAAEPVTPP RVTWLRAGDT EIRTALLLPS WHRPGAAPLP
     VLLAPYAGPA QRLVLRGRNW PLCEAQWFAE EGFAVIVADG RGTPGRGPRW EKSVHLDTLA
     APLDDQVTAL HAAAAHCPDL DLERVGIRGW SYGGTLAAAA VLRRPDVFHA AVCGAGPSDQ
     RLYDTHWRER FLGHPDEHPE AYERSSPINE AAALRRPLLL VHGMADDNVV AAHTLRMSAA
     LLAAHRPHQV LPMSDVTHGP TDPVVVEGLL RHQLNFLRAS LNVSPPQAV
//