ID   A0A1H8KC72_9ACTN        Unreviewed;       924 AA.
AC   A0A1H8KC72;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Alpha-1,2-mannosidase, putative {ECO:0000313|EMBL:SEN90580.1};
GN   ORFNames=SAMN05216267_1012127 {ECO:0000313|EMBL:SEN90580.1};
OS   Actinacidiphila rubida.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Actinacidiphila.
OX   NCBI_TaxID=310780 {ECO:0000313|EMBL:SEN90580.1, ECO:0000313|Proteomes:UP000181951};
RN   [1] {ECO:0000313|EMBL:SEN90580.1, ECO:0000313|Proteomes:UP000181951}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.2026 {ECO:0000313|EMBL:SEN90580.1,
RC   ECO:0000313|Proteomes:UP000181951};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FODD01000012; SEN90580.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8KC72; -.
DR   STRING; 310780.SAMN05216267_1012127; -.
DR   Proteomes; UP000181951; Unassembled WGS sequence.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd00161; RICIN; 1.
DR   Gene3D; 2.70.98.10; -; 1.
DR   Gene3D; 2.80.10.50; -; 2.
DR   Gene3D; 1.20.1050.60; alpha-1,2-mannosidase; 1.
DR   Gene3D; 1.20.1610.10; alpha-1,2-mannosidases domains; 1.
DR   Gene3D; 3.30.2080.10; GH92 mannosidase domain; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR005887; GH92_a_mannosidase_put.
DR   InterPro; IPR041371; GH92_N.
DR   InterPro; IPR012939; Glyco_hydro_92.
DR   InterPro; IPR035992; Ricin_B-like_lectins.
DR   InterPro; IPR000772; Ricin_B_lectin.
DR   NCBIfam; TIGR01180; aman2_put; 1.
DR   NCBIfam; NF035929; lectin_1; 1.
DR   PANTHER; PTHR12143; PEPTIDE N-GLYCANASE PNGASE -RELATED; 1.
DR   PANTHER; PTHR12143:SF39; SECRETED PROTEIN-RELATED; 1.
DR   Pfam; PF07971; Glyco_hydro_92; 1.
DR   Pfam; PF17678; Glyco_hydro_92N; 1.
DR   Pfam; PF00652; Ricin_B_lectin; 1.
DR   SMART; SM00458; RICIN; 1.
DR   SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR   PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000181951};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           33..924
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5010205613"
FT   DOMAIN          794..923
FT                   /note="Ricin B lectin"
FT                   /evidence="ECO:0000259|SMART:SM00458"
FT   REGION          227..278
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        228..249
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        264..278
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   924 AA;  95444 MW;  776F430980FB3F96 CRC64;
     MKRLSSSPGA AVIGVLATAA LAVAGMCAPA TAAAKPALVT SPATVVNPFI GTSNQANDFP
     GADVPFGMVQ WSPDTTSRPP GGGYEYNDSS ITGFSLTHIA GPGCGAAGDV PVLPTVGAVN
     TGATDAFSHA NESASAGSYK VALNNQVTTE LTTTTRSGMA RFTFPKTTQA NLVFKLTSSQ
     NGASSTQFTK VSSTEVSGQV TSGHFCGAGN TYTVYFDMVF DQPFAGQGSS AAKPTASAPA
     TTGTASKNAA EKPNKPVLHG KAPAATTSDT TKGSASPNAA ASNGYVTFDT SSNPVVQAKV
     GVSYVSVANA VANRTAENSG WNFDTTRTAA QNSWNSLLGR VQIAGGTTAQ QQSFYTALYH
     SLLHPNVISD TNGQYYGFDG KTHTVDSGHS AVYANYSGWD IYRSQAQLEG LMAPQVASDT
     AQSMVDDYTQ TGQFPKWSED NGESYVMVGD PADGILADYY AFGATSFDTS TALTDMVAEA
     SKTNNDRPGL NYLNSPGYMP HDGSYGCCNF YGPVATTLEY NTADFALSAM AGALGDTTDQ
     KTYASRAQDW RNVLNPASGF VEPRNASGAW TGGFDPTSGT DMVEADSWIY TGMVPFDIGG
     LAHAKGGNAA MNDYLDTTLR SYTGANGYAW VGNEPSIELP WEYDYIGEPY KTQGTVRSIQ
     DQIWADTPGG LADGNDDLGA MSAWYVWSAL GMFPETPGTS DLALGSPLFT QAVITLPSGQ
     TLTVNGNGAA DNAPYVQSAT WNGAAWNNAY APTTAITAGG TLNYTLGTAA NTSWATAASA
     APPSYAGGTT APASPRIGAI GAGVGTNLCL DDANSATADG THAQIWGCDS TYAQDWIIAS
     DSTLRTLGKC LDVSNSGTTN GTLVQLWTCN GTGAQKWTPG ANGSLVNPQS GLCLDVPNSS
     TTNGTQVQLY TCNGSGAQNW KLPS
//