ID A0A1H8KRH5_9BACT Unreviewed; 1343 AA.
AC A0A1H8KRH5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Amino acid adenylation domain-containing protein {ECO:0000313|EMBL:SEN95487.1};
DE Flags: Fragment;
GN ORFNames=SAMN04488505_1201 {ECO:0000313|EMBL:SEN95487.1};
OS Chitinophaga rupis.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Chitinophaga.
OX NCBI_TaxID=573321 {ECO:0000313|EMBL:SEN95487.1, ECO:0000313|Proteomes:UP000198984};
RN [1] {ECO:0000313|EMBL:SEN95487.1, ECO:0000313|Proteomes:UP000198984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21039 {ECO:0000313|EMBL:SEN95487.1,
RC ECO:0000313|Proteomes:UP000198984};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR EMBL; FOBB01000020; SEN95487.1; -; Genomic_DNA.
DR STRING; 573321.SAMN04488505_1201; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000198984; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR CDD; cd05930; A_NRPS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SMART; SM01294; PKS_PP_betabranch; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 3.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000198984}.
FT DOMAIN 754..829
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT NON_TER 1343
FT /evidence="ECO:0000313|EMBL:SEN95487.1"
SQ SEQUENCE 1343 AA; 149328 MW; 1F3D1813165BEB40 CRC64;
MLSVDNAVFT GSRYQPYIAY WKQLLQRHAH TCRQAVRPPD ESNCSTFTFR LSREDAPPLF
ALGAGNRTAL MLNLLSAFAV VCSRYSSRET VIIDTPLHNN STAPKYAAKV PLLLTVDAKA
TLHEYLSTCQ RTVRDAYRFQ DFPASLLETY GKASTDIFFS FEDWHLPATA AGGYALVIHA
AQKGDELEVM LQGDAEAFEP LFLEHMKQHI CAVLNAMANL QRTLAQVTLL SEDAARQLLD
TYSGTTAVYP VDETITTLFE RQAAATPQHT AVIAGSSSLS YAALNAAANQ LAHGLRGEYG
VQHGDVVAIV TDRSELVVIA MLAILKAGAT YLPVESTLPE ERIRYMLQDA GAKLLVTGSR
QMLQAAAYFS GPLFVLDIQL AALTTPAANL PPAATPASAA YIIYTSGTTG YPKGVVIPHA
AQVNMCYGQM ERFGITAADK ILQSASLSFD VCGFEIFMAL YAGATVVIAD RDLVNDGTAL
LQYMQQHQVT VAAFTASYLQ VLPVMELYSL RVLITGGEAV HAATLAALPA NVQFHNAYGP
TECTVCAATY NISAGTEAYW PVPLGKPLPN IRMYILDQQL QPVPAGMKGE LCISGICLAN
GYLGQPELTA EKFVPHPFLP GERLYRTGDV ARWLPDGNVV YCGRMDGQVK INGNRVETAE
IEAVLMLQPG ITKVLVLPLT ENERTQLAAY IQAVGELDED QLKEKLSALL PAYMVPAFFI
PLKEFPLTAN GKVDTAALPS PRQPATEAAV AYEAPANDTE EKLCNLWKEI LRKETIGVTE
NFFSLGGDSL KAIQMVTAIN RLFGRPVPVD KIYTGPTIRE LAAFLGQDAG ASSLYHDLEK
GTLLLEDFAR RITAENKEAL PAGYEDLYPV TPIEAGMIYS SLLEPEKPVY YDQYNFQLEL
SSFALFESAF TFLAHRHPML RTFFFMSGFS EPLKVVVRNP TLPVTMEDLS HHPYDTQLQL
VKEYLQADRN NRFHFDGELL WRLKAFRLSE KQFYIVWSTH HAMLDGWGKN QLKTEMGKLL
AGNNGLLDMQ ALQPLKYSYR DYCAITLGRK YTEAAKHYWQ QTLDGSIRNR LPFNYAGKQL
NDDKSMPVQA KILDRELLNK LELMCKEQQV SFKALAMAAF AYLMHILCAE EDVITGVVSH
DRPALEDSDK ILGCFLTTIP VRLQVKEAHD YLSLITLAQQ YLLDVKPHEM HLTDIAKVTG
IQTTAHSPFF SCMLNYTDFF VLEEYEDSDN MSLQRYFQED AALLDFGMTN TLLDIEIGKT
TQTLGISIRY RAAYFREEDM KYALEIYERI LRNIAADVRQ PLHTAALMDG ATQRWLTYDF
NNTLHPYDDS IRLESLLSRQ AAV
//
