ID   A0A1H8LIK9_9ACTN        Unreviewed;       400 AA.
AC   A0A1H8LIK9;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Two-component system, OmpR family, sensor histidine kinase KdpD {ECO:0000313|EMBL:SEO04937.1};
GN   ORFNames=SAMN05216267_101627 {ECO:0000313|EMBL:SEO04937.1};
OS   Actinacidiphila rubida.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Actinacidiphila.
OX   NCBI_TaxID=310780 {ECO:0000313|EMBL:SEO04937.1, ECO:0000313|Proteomes:UP000181951};
RN   [1] {ECO:0000313|EMBL:SEO04937.1, ECO:0000313|Proteomes:UP000181951}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.2026 {ECO:0000313|EMBL:SEO04937.1,
RC   ECO:0000313|Proteomes:UP000181951};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FODD01000016; SEO04937.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8LIK9; -.
DR   STRING; 310780.SAMN05216267_101627; -.
DR   OrthoDB; 9806130at2; -.
DR   Proteomes; UP000181951; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd01987; USP_OKCHK; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR   InterPro; IPR006016; UspA.
DR   PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR   PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR   Pfam; PF02702; KdpD; 1.
DR   Pfam; PF00582; Usp; 1.
DR   SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SEO04937.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000181951};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   DOMAIN          12..220
FT                   /note="Signal transduction histidine kinase osmosensitive
FT                   K+ channel sensor N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02702"
FT   DOMAIN          241..364
FT                   /note="UspA"
FT                   /evidence="ECO:0000259|Pfam:PF00582"
FT   REGION          374..400
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   400 AA;  44062 MW;  92860D8C863BA8CD CRC64;
     MEEDAEGVVA VRGTLRVYLG AAPGVGKTYD MLAEGHRRAG RGTDVVIAYM EDYGRPLTRQ
     MAEGLEAVPR RTMEYRGCTF TEMDLDAVLA RHPRVALVDE MAHTNIPGSR NEKRWQDVHE
     LLAAGIHVIS TVNIQHLESL NDVVAHITGV KQRETVPDDV VRGADQIELV DMSAEALRRR
     MAHGNIYPRE KVELALAHYF RVGNLSALRE IALLWAADRV EEALLRYRHD HGIQQPWATR
     ERVLVALSGG PEGDTLIRRA KRTASRGAGG EFLALHVEPD DALATRTQRL PARQRELVEE
     LGGTCHMIAG SDPARVILDF AREVNASQIL IGATRRSRVH RFLSRGIGET IIEGSGDDID
     VLVVTHSEAA HGRWLRRRSG GAESSDEAEE GGGDGEDAPC
//