ID   A0A1H8MVY7_9BURK        Unreviewed;       374 AA.
AC   A0A1H8MVY7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Histone methylation protein DOT1 {ECO:0000313|EMBL:SEO21398.1};
GN   ORFNames=SAMN05428959_105391 {ECO:0000313|EMBL:SEO21398.1};
OS   Duganella sp. CF517.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Oxalobacteraceae; Telluria group; Duganella.
OX   NCBI_TaxID=1881038 {ECO:0000313|EMBL:SEO21398.1, ECO:0000313|Proteomes:UP000198691};
RN   [1] {ECO:0000313|Proteomes:UP000198691}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CF517 {ECO:0000313|Proteomes:UP000198691};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FODC01000005; SEO21398.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8MVY7; -.
DR   STRING; 1881038.SAMN05428959_105391; -.
DR   Proteomes; UP000198691; Unassembled WGS sequence.
DR   GO; GO:0031151; F:histone H3K79 methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR025789; DOT1_dom.
DR   InterPro; IPR026170; FAM173A/B.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR13610:SF11; METHYLTRANFER_DOM DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR13610; UNCHARACTERIZED; 1.
DR   Pfam; PF08123; DOT1; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198691};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          144..209
FT                   /note="DOT1"
FT                   /evidence="ECO:0000259|Pfam:PF08123"
SQ   SEQUENCE   374 AA;  41144 MW;  B753349773FDDCD3 CRC64;
     MRLPHLKPPM NSHTMPPVFR TEDGPVTPVA SFKQPADIFE ALFQSIQGGE KHVRPLLDLV
     PDSRFLGFIE VGYALRACLE DKSRRDYLLQ RLRPHLGVII GTLPASIQPH GMLPKQPAPP
     GFRDLEQIGD DEIRAWLIED GGLIYGEFAR YELDNLFDAI APAIRPGGVM VDLGSGLGKV
     VMSAALAFPF QRCVGVECMG YRHRMALQRL HNLLVLAERG VAHLPTPLTA NAPLTLPFGD
     ATTGSHLLDL ASRISFVESD MFKVDVHGAS LVFLYSTCFG PLMDALADKL ARELQEGALV
     TTTTYALKHP AFTLLHYFPA GTVAWTNVML YKRTGKLESL PPADITHPHQ PDADEWEARA
     RQDLDAMDAR AGTA
//