ID A0A1H8P3L2_9RHOB Unreviewed; 335 AA.
AC A0A1H8P3L2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Glyoxylate reductase {ECO:0000313|EMBL:SEO36427.1};
GN ORFNames=SAMN04489859_10794 {ECO:0000313|EMBL:SEO36427.1};
OS Paracoccus alcaliphilus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Paracoccus.
OX NCBI_TaxID=34002 {ECO:0000313|EMBL:SEO36427.1, ECO:0000313|Proteomes:UP000199054};
RN [1] {ECO:0000313|EMBL:SEO36427.1, ECO:0000313|Proteomes:UP000199054}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8512 {ECO:0000313|EMBL:SEO36427.1,
RC ECO:0000313|Proteomes:UP000199054};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00005854,
CC ECO:0000256|RuleBase:RU003719}.
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DR EMBL; FODE01000079; SEO36427.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H8P3L2; -.
DR STRING; 34002.SAMN04489859_10794; -.
DR OrthoDB; 9793626at2; -.
DR Proteomes; UP000199054; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05301; GDH; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029753; D-isomer_DH_CS.
DR InterPro; IPR029752; D-isomer_DH_CS1.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
DR PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000199054}.
FT DOMAIN 20..330
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 120..299
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 335 AA; 36963 MW; ADB35C63DE3F3140 CRC64;
MSSNPSSPAR QRLRISVTRR LPETVETRMS ELFDVSLNES DRRMSRDELV VAMQNCDVLV
PTVTDHIDAN MLAQAGGRLK LIANYGAGVD HIDVLSARQR GILVSNTPGV VTEDTADMVM
ALILSVTRRI PEGMAEMQAG RWQGWAPTAH LGGRVGGRRL GILGMGRIGQ AVARRANVFG
MQVHYHNRKR LRPEIEADLQ ATWWESLDQM LARMDIVSVN APHTPSTFHL LNARRLKLLK
PSAVVVNTSR GEVIDENALT RMLRAGEIAG AGLDVFEHGH EINPRLRELP NVVLLPHMGS
ATVEGRAEMG EKVIINIKTF DDGHRPPDLV VPSML
//
