ID   A0A1H8QYM8_9ACTN        Unreviewed;       803 AA.
AC   A0A1H8QYM8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Competence protein ComEC {ECO:0000313|EMBL:SEO58978.1};
GN   ORFNames=SAMN05660991_00871 {ECO:0000313|EMBL:SEO58978.1};
OS   Trujillella endophytica.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Trujillonella.
OX   NCBI_TaxID=673521 {ECO:0000313|EMBL:SEO58978.1, ECO:0000313|Proteomes:UP000198960};
RN   [1] {ECO:0000313|EMBL:SEO58978.1, ECO:0000313|Proteomes:UP000198960}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45413 {ECO:0000313|EMBL:SEO58978.1,
RC   ECO:0000313|Proteomes:UP000198960};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FOEE01000002; SEO58978.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8QYM8; -.
DR   STRING; 673521.SAMN05660991_00871; -.
DR   Proteomes; UP000198960; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   CDD; cd07731; ComA-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR035681; ComA-like_MBL.
DR   InterPro; IPR004477; ComEC_N.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   NCBIfam; TIGR00360; ComEC_N-term; 1.
DR   PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR   PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR   Pfam; PF03772; Competence; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        49..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        237..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        268..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        308..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        331..350
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        362..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        402..420
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        458..477
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        484..500
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          521..716
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
FT   REGION          759..803
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   803 AA;  80828 MW;  9D2D79E2768C4659 CRC64;
     MWTDLRLVPA AAGAWALTLA APSVSWQVLA VLAGAAAAAA GALTRGRPAG AALVVSAVLA
     VLSLTAAGAA ARSWDRAGSP LPGAGGTVML ELETDSDPRR VAGVGPPRVV VEATVTRLSD
     GADAVVLDDR VVVFAPAEGW AGLLPGQALR TRAAVGPADP ADGVAARVSA RGLPELLGRP
     PWVQRAAGDL RAALASSAAR TLDQPAAGLL PGLVVGDTTE LDPVLAEEFR RAGLSHLTAV
     SGANVAIVLA GVLAPLRRRA VDRRAQAVVA GLALAGFVLL ARPTASVLRA AAMGAVSLLA
     LASGRSRVAV PALSATVVVL LLVDPRLARD AGFALSVAAT AAIVLLAPGW SRRLRTHGWP
     RLLADAVAVS SAAGLATAPL IAGLSGEVSL VSLPANLLAA PAVPPATVLG LLAAGAGPLA
     APLADCLTWL AGWPVRWLVL VARTAAGLPD AATGWPAGST GALVLTGLLA IGALALWRWP
     RLRALALALV VGAVLLGWPL RQVTRGWPPA GAVLVACDVG QGDALVVPTG PGEAVLVDAG
     PEVAPIDRCL DRLGIDRLPV VLLSHLDADH VGGLAGALAG REVGVVATGM LSPADDRGAA
     LSRAAREAGA RQEVLVPGER RRIGPATVEV LAPAPEIATA SADPNDLSLV LRVTVRGLRV
     LLTGDLSAQA EQRLMRRGVD LRADVLKVPH HGSADNDPDF LAASGARVAL VSVGADNTYG
     HPTRRLLGWL SRAGMRVYRT DRSGDVAVAG TAGEWAVVPR GADGSTAAPS AEASEPSSQP
     LPAPMPARPG AGPWRRPGTV GGS
//