ID A0A1H8RS86_9ACTN Unreviewed; 649 AA.
AC A0A1H8RS86;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Succinate dehydrogenase subunit A {ECO:0000313|EMBL:SEO69222.1};
GN ORFNames=SAMN05216267_103667 {ECO:0000313|EMBL:SEO69222.1};
OS Actinacidiphila rubida.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Actinacidiphila.
OX NCBI_TaxID=310780 {ECO:0000313|EMBL:SEO69222.1, ECO:0000313|Proteomes:UP000181951};
RN [1] {ECO:0000313|EMBL:SEO69222.1, ECO:0000313|Proteomes:UP000181951}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.2026 {ECO:0000313|EMBL:SEO69222.1,
RC ECO:0000313|Proteomes:UP000181951};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FODD01000036; SEO69222.1; -; Genomic_DNA.
DR RefSeq; WP_069464606.1; NZ_MDCQ01000458.1.
DR AlphaFoldDB; A0A1H8RS86; -.
DR STRING; 310780.SAMN05216267_103667; -.
DR OrthoDB; 9805351at2; -.
DR Proteomes; UP000181951; Unassembled WGS sequence.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR011280; Succ_DH/Fum_Rdt_flav_su.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01811; sdhA_Bsu; 1.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF53; SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000181951}.
FT DOMAIN 47..452
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 514..648
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 341
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR630664-50"
SQ SEQUENCE 649 AA; 71763 MW; C7E2419B690962B5 CRC64;
MDHYTQYETG APLADTKAPD GPIAERWDAR RFGARLVNPA NRRKHTVIVV GTGLAGGSAG
ATLAEQGYHV VQFCYQDSPR RAHSIAAQGG INAAKNYRND GDSIQRLFYD TVKGGDFRAR
ESNVHRLAQI SVEIIDQCVA QGVPFAREYG GLLDTRSFGG VQVSRTFYAR GQTGQQLLLG
AYQALSRQIA AGTVEMHPRT EMLDLIVVDG RARGIVARDL VTGEIGTYFA DAVVLASGGY
GNVFYLSTNA MNSNATAIWR AHRRGAQFAN PCFTQIHPTC IPRTGEHQSK LTLMSESLRN
DGRIWVPKAE GDTRAPGDIP EAERDYYLER IYPSFGNLVP RDIASRAAKN VCDEGRGVGP
GGQGVYLDFA DAIARMGRRA VEEKYGNLFE MYQRITAEDP YEVPMRIYPA VHYTMGGLWV
DYDLQTTVPG LFAIGEANFS DHGANRLGAS ALMQGLADGY FVLPATINDY LARHPHQDPV
DPTHPEVTAA LAETGDRLHR LVSVDGDRTA DSFHREIGAL MWEYCGMARN EEGLRKALDR
IPQIREEFWR RIKVPGTEAE FNQSLERANR VVDYLELAEL MCLDALHRAE SCGGHFREES
QTPDGEAARD DDAFSYAAAW EFTGTGQPPV LHKEDLVFDH VHPTQRSYA
//
