ID   A0A1H8SFI1_9PSEU        Unreviewed;       472 AA.
AC   A0A1H8SFI1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Glutamate or tyrosine decarboxylase {ECO:0000313|EMBL:SEO76933.1};
GN   ORFNames=SAMN04489732_10262 {ECO:0000313|EMBL:SEO76933.1};
OS   Amycolatopsis saalfeldensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=394193 {ECO:0000313|EMBL:SEO76933.1, ECO:0000313|Proteomes:UP000198582};
RN   [1] {ECO:0000313|EMBL:SEO76933.1, ECO:0000313|Proteomes:UP000198582}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44993 {ECO:0000313|EMBL:SEO76933.1,
RC   ECO:0000313|Proteomes:UP000198582};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR602129-50, ECO:0000256|RuleBase:RU000382};
CC   -!- SIMILARITY: Belongs to the group II decarboxylase family. Sphingosine-
CC       1-phosphate lyase subfamily. {ECO:0000256|ARBA:ARBA00038302}.
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DR   EMBL; FOEF01000002; SEO76933.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8SFI1; -.
DR   STRING; 394193.SAMN04489732_10262; -.
DR   OrthoDB; 3401800at2; -.
DR   Proteomes; UP000198582; Unassembled WGS sequence.
DR   GO; GO:0016831; F:carboxy-lyase activity; IEA:UniProt.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR42735; -; 1.
DR   PANTHER; PTHR42735:SF6; SPHINGOSINE-1-PHOSPHATE LYASE 1; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU000382};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50,
KW   ECO:0000256|RuleBase:RU000382};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198582}.
FT   MOD_RES         230
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602129-50"
SQ   SEQUENCE   472 AA;  48855 MW;  19EEBAF3DE648D0F CRC64;
     MNEVLAQLRE LRAGDLPTHG GRTLAYVYDS GLSEVDEIAA AAHALASSAN GLDPTAFPSL
     LRMENDLVAT AAGLLGGDAE TVGTVTSGGT ESCLLAVLAA RDARPGLAAP GLVLAETAHA
     AFHKAAHLFG VRKVVVPVDP VTFRADPAAM AAAIDESTVL VVASAPSYAH GVVDPIPEIA
     AAAAARGVRM HVDGCIGAWV LPYLARLGAD VPPFDFRVPG VTSISVDLHK YAYCAKGVSV
     LLHANAGLRR THYFASADWP GYTMLNPTLQ STRSGGPLAA AWAVVRHLGD EGYLRLAEVT
     REAVARIRAG IEGINGLRVL GDPDSTLIAF TAAAPGFDLF TVADEMKVRG WYVQPQFAHG
     SSPLNLHLTV TAANHGSEAE FLADLTASVL AAKSAGPVTV DPDVAAFVAA LDPETLTTEQ
     FGDLLAAAGL TGGDGLPDRM APINALLATA AEPLRERLLL EFLGALYTPG PH
//