ID   A0A1H8TAN9_9FIRM        Unreviewed;       456 AA.
AC   A0A1H8TAN9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Putative MFS transporter, AGZA family, xanthine/uracil permease {ECO:0000313|EMBL:SEO88160.1};
GN   ORFNames=SAMN04490178_10697 {ECO:0000313|EMBL:SEO88160.1};
OS   Propionispora vibrioides.
OC   Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC   Propionispora.
OX   NCBI_TaxID=112903 {ECO:0000313|EMBL:SEO88160.1, ECO:0000313|Proteomes:UP000198847};
RN   [1] {ECO:0000313|EMBL:SEO88160.1, ECO:0000313|Proteomes:UP000198847}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13305 {ECO:0000313|EMBL:SEO88160.1,
RC   ECO:0000313|Proteomes:UP000198847};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC       Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC       ECO:0000256|PIRNR:PIRNR005353}.
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DR   EMBL; FODY01000006; SEO88160.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8TAN9; -.
DR   STRING; 112903.SAMN04490178_10697; -.
DR   OrthoDB; 9808458at2; -.
DR   Proteomes; UP000198847; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR   InterPro; IPR045018; Azg-like.
DR   InterPro; IPR026033; Azg-like_bact_archaea.
DR   InterPro; IPR006043; NCS2.
DR   PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR   PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PIRSF; PIRSF005353; PbuG; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198847};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT   TRANSMEM        21..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        49..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        83..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        134..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        218..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        251..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        306..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        341..362
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        397..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        438..455
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   456 AA;  47622 MW;  EFD9FC4136DA635B CRC64;
     MLEKLFALKA RKTDVNTEVM AGITTFMTMA YILFVNPSIL GSAGMDKNAV LLATAIGAGA
     VTIMMGLFVN YPIALAPGMG LNAFYAFTVV IGMGVSWQVA LGAVFISGLI FILLTVTKVR
     QLLVEGMPAS LKHAISVGIG LFITIIGLKL SGLMSIRLSL IPPTLEKLVA AHGNGTPLSF
     ETIIEMGKLA DKEVLLAVFG LLFIGVLIAR NIKGSMLIGI LVTTILGVVM GVVKIPAGFS
     PVAVPDFSQN AFFALDIMGA VHMGLLTIIF TFTFVELFDT MGTLVGTATK AGLMDKNGNF
     PGIGKAMLVD ATGVSLGALL GTSTITAYVE SAAGVGAGGR SGLTAVVCGL LFFAALFFSP
     LAGLIPDAAT APALIIVGAL MMESVRHIDF GDFTEALPAF LTIVMMPFTY SIANGVSAGL
     VVYPLVKLIT GRGREVHWII YVLAVLVVAR FVFLAE
//