ID A0A1H8U914_9ACTN Unreviewed; 355 AA.
AC A0A1H8U914;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:SEO99148.1};
GN ORFNames=SAMN05216267_106526 {ECO:0000313|EMBL:SEO99148.1};
OS Actinacidiphila rubida.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Actinacidiphila.
OX NCBI_TaxID=310780 {ECO:0000313|EMBL:SEO99148.1, ECO:0000313|Proteomes:UP000181951};
RN [1] {ECO:0000313|EMBL:SEO99148.1, ECO:0000313|Proteomes:UP000181951}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.2026 {ECO:0000313|EMBL:SEO99148.1,
RC ECO:0000313|Proteomes:UP000181951};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FODD01000065; SEO99148.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H8U914; -.
DR STRING; 310780.SAMN05216267_106526; -.
DR OrthoDB; 3595338at2; -.
DR Proteomes; UP000181951; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR001761; Peripla_BP/Lac1_sug-bd_dom.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF138; HTH-TYPE TRANSCRIPTIONAL REGULATOR KDGR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF00532; Peripla_BP_1; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000181951};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 25..79
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 355 AA; 38025 MW; F7307396DD5CD12A CRC64;
MSGADGRRDP RNPRNADASR PVPRPRMQDI ADATGVTIKT VSRALSDAPN VRRSTRERIL
AEAERLGFRR NDIAAGLRST GQTMRTLGVV LGDLANPFFP PMLRGIHEVA ARHGYLVITA
DAQGDAAVER ESIQAILSQR VAGLVIAPTG TDFGYLAQEA RFGSAIVFID SAPLGLTADA
VVTTNTAGTR GAVAHLIGRG HRRIGYLGHP PHGHGAPKRW AGYTLALRQA GLPVDDALVR
RGLTTEAEAC RAAGELLGLD DPPTALFADN NRMTMGVLRS PLYAVRRPEV VGFDHFDLAP
QLGISVVDSD PFRVGSAGAE LLFRRLADRG RPPMQTTVRA KLIVHDRPTF TAVAP
//
