ID   A0A1H8VUV8_9RHOB        Unreviewed;       306 AA.
AC   A0A1H8VUV8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=inorganic diphosphatase {ECO:0000256|ARBA:ARBA00012146};
DE            EC=3.6.1.1 {ECO:0000256|ARBA:ARBA00012146};
DE   AltName: Full=Pyrophosphate phospho-hydrolase {ECO:0000256|ARBA:ARBA00032535};
GN   ORFNames=SAMN04490248_13510 {ECO:0000313|EMBL:SEP19232.1};
OS   Salinihabitans flavidus.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Salinihabitans.
OX   NCBI_TaxID=569882 {ECO:0000313|EMBL:SEP19232.1, ECO:0000313|Proteomes:UP000198893};
RN   [1] {ECO:0000313|EMBL:SEP19232.1, ECO:0000313|Proteomes:UP000198893}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 27842 {ECO:0000313|EMBL:SEP19232.1,
RC   ECO:0000313|Proteomes:UP000198893};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=diphosphate + H2O = H(+) + 2 phosphate; Xref=Rhea:RHEA:24576,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:43474; EC=3.6.1.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00000926};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|ARBA:ARBA00001936};
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DR   EMBL; FODS01000035; SEP19232.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8VUV8; -.
DR   STRING; 569882.SAMN04490248_13510; -.
DR   OrthoDB; 9766150at2; -.
DR   Proteomes; UP000198893; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0004427; F:inorganic diphosphate phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.310.20; DHHA2 domain; 1.
DR   Gene3D; 3.90.1640.10; inorganic pyrophosphatase (n-terminal core); 1.
DR   InterPro; IPR001667; DDH_dom.
DR   InterPro; IPR038763; DHH_sf.
DR   InterPro; IPR004097; DHHA2.
DR   InterPro; IPR038222; DHHA2_dom_sf.
DR   PANTHER; PTHR12112; BNIP - RELATED; 1.
DR   PANTHER; PTHR12112:SF22; MANGANESE-DEPENDENT INORGANIC PYROPHOSPHATASE; 1.
DR   Pfam; PF01368; DHH; 1.
DR   Pfam; PF02833; DHHA2; 1.
DR   SMART; SM01131; DHHA2; 1.
DR   SUPFAM; SSF64182; DHH phosphoesterases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Manganese {ECO:0000256|ARBA:ARBA00023211};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198893}.
FT   DOMAIN          181..304
FT                   /note="DHHA2"
FT                   /evidence="ECO:0000259|SMART:SM01131"
SQ   SEQUENCE   306 AA;  32734 MW;  5983A0D83563D32C CRC64;
     MTIKVFGHKS PDTDSTGSPI LWAWYLNEVK GETAEAVLLG EPSSEAAFML ERWNLPKPAI
     ISDIEEDAPC VVVDTNNPAE LPANINKADV QAIIDHHKLA GGLETKAPID ITIRPLACTA
     TIMIDLMGED AAKMPDWAKG AALTCILSDT LEFRSPTTTP HDRAVAEGLA SDLGIDIAAY
     AADMFAAKSD VSAFSDAELL RMDSKEYTVD GTKFRVSVLE TTAPGIVLDR KDSLAEAMKT
     VATEDGVDQV LLFVVDILNE EATLLVPNDL VKSVAEKSFG ASIAGDTVVL PGVMSRKKQI
     IPNLKV
//