ID   A0A1H8WCK6_9FIRM        Unreviewed;       248 AA.
AC   A0A1H8WCK6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Cysteine protease, C1A family {ECO:0000313|EMBL:SEP25402.1};
GN   ORFNames=SAMN04490178_11550 {ECO:0000313|EMBL:SEP25402.1};
OS   Propionispora vibrioides.
OC   Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC   Propionispora.
OX   NCBI_TaxID=112903 {ECO:0000313|EMBL:SEP25402.1, ECO:0000313|Proteomes:UP000198847};
RN   [1] {ECO:0000313|EMBL:SEP25402.1, ECO:0000313|Proteomes:UP000198847}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13305 {ECO:0000313|EMBL:SEP25402.1,
RC   ECO:0000313|Proteomes:UP000198847};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase C1 family.
CC       {ECO:0000256|ARBA:ARBA00008455}.
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DR   EMBL; FODY01000015; SEP25402.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8WCK6; -.
DR   STRING; 112903.SAMN04490178_11550; -.
DR   OrthoDB; 3648721at2; -.
DR   Proteomes; UP000198847; Unassembled WGS sequence.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd02619; Peptidase_C1; 1.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR025660; Pept_his_AS.
DR   InterPro; IPR013128; Peptidase_C1A.
DR   InterPro; IPR000668; Peptidase_C1A_C.
DR   PANTHER; PTHR12411:SF741; CATHEPSIN K; 1.
DR   PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR   Pfam; PF00112; Peptidase_C1; 1.
DR   SMART; SM00645; Pept_C1; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:SEP25402.1};
KW   Protease {ECO:0000313|EMBL:SEP25402.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198847}.
FT   DOMAIN          29..239
FT                   /note="Peptidase C1A papain C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00645"
SQ   SEQUENCE   248 AA;  28042 MW;  39CA306B3BE416DF CRC64;
     MPKYLLKKDS PDLRDYIFYS SKYKLIEHLP AKIDLRSNCS PVVDQGELGS CTANAIASGL
     REYWELKSTQ SLITLSRLFL YYKERELEGQ VNEDSGAEIR DGMKVLSQIG VCPETDWPYD
     IATFKNAPTD KQTTDAAIYK VNEYHRIILF SQIKAALAEE LPVVIGIKVY DSFESDEVAQ
     TGLVPMPNPG KEQYLGGHAV LIVGYDDSSK VFIVRNSWGT SWGDKGYCYL PYQYYTQGYI
     SDCWTSKG
//