ID A0A1H8X5W3_9PROT Unreviewed; 581 AA.
AC A0A1H8X5W3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=SAMN02990966_05262 {ECO:0000313|EMBL:SEP35289.1};
OS Rhodospirillales bacterium URHD0017.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales.
OX NCBI_TaxID=1380357 {ECO:0000313|EMBL:SEP35289.1, ECO:0000313|Proteomes:UP000198826};
RN [1] {ECO:0000313|EMBL:SEP35289.1, ECO:0000313|Proteomes:UP000198826}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=URHD0017 {ECO:0000313|EMBL:SEP35289.1,
RC ECO:0000313|Proteomes:UP000198826};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FODP01000013; SEP35289.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H8X5W3; -.
DR STRING; 1380357.SAMN02990966_05262; -.
DR OrthoDB; 9801841at2; -.
DR Proteomes; UP000198826; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00143; PP2Cc; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008266; Tyr_kinase_AS.
DR PANTHER; PTHR43289; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED; 1.
DR PANTHER; PTHR43289:SF32; SERINE_THREONINE-PROTEIN KINASE PKAB; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13672; PP2C_2; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51746; PPM_2; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:SEP35289.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:SEP35289.1};
KW Transferase {ECO:0000313|EMBL:SEP35289.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 553..575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..238
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT DOMAIN 271..539
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 581 AA; 64368 MW; F0B8809E4ABDC061 CRC64;
MARDLKISIG QHTDKGRKES NQDFHGAMMP PQPALGSKGV AVALADGISS SSVSRVASES
AVKGFLTDYY CTSDAWSVKT SAQRVIDATN SWLHSQTRRS HVEDADRGYV CTLNVVVLKG
RTAHIFHIGD SRVYRVAGTA MEQLTDDHRV VLSSEQIYLG RALGMSPQVE IDYRPIQLEE
GDLFLQATDG VCEHLDARVV ADAIAANEND LDGAAKAIVA EAFRRGSPDN LTVQLVRIDA
LPEGDAEESL GIGADLPVPP LLEPRQLFDG YRIVRTIHGS SRSHAYLAVD GESNETVVLK
IPSIDLRADP ANLKPFMMEE WIARRLNSAH VLRPQQHTRK RNFLYVVTEF VDGQTLRQWM
IDNRRPDLET VRGIVEQIAR GLRAFHRMEM LHQDLRPENV MIDKTGTVKI IDFGAVRVAG
VAETERPADR DRIKGTAQYT APEYFLGEGG SPSSDLFSLG VIAYEMLTGR LPYGARMATA
RSRAQQRSTP YAPAIDAESE IPAWIDATLR KAVHPDPNKR YGELSEFIFD LRHPNESFLR
ASTAPLIERN PLAFWKGLSF VLGCTALALL ALLVFRIPLP R
//
