ID A0A1H8XSM0_9FIRM Unreviewed; 742 AA.
AC A0A1H8XSM0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=ATP-binding cassette, subfamily B, HlyB/CyaB {ECO:0000313|EMBL:SEP42762.1};
GN ORFNames=SAMN04490178_12854 {ECO:0000313|EMBL:SEP42762.1};
OS Propionispora vibrioides.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC Propionispora.
OX NCBI_TaxID=112903 {ECO:0000313|EMBL:SEP42762.1, ECO:0000313|Proteomes:UP000198847};
RN [1] {ECO:0000313|EMBL:SEP42762.1, ECO:0000313|Proteomes:UP000198847}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13305 {ECO:0000313|EMBL:SEP42762.1,
RC ECO:0000313|Proteomes:UP000198847};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FODY01000028; SEP42762.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H8XSM0; -.
DR STRING; 112903.SAMN04490178_12854; -.
DR OrthoDB; 9762778at2; -.
DR Proteomes; UP000198847; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030256; C:type I protein secretion system complex; IEA:InterPro.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:InterPro.
DR GO; GO:0030253; P:protein secretion by the type I secretion system; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd18588; ABC_6TM_CyaB_HlyB_like; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR010132; ATPase_T1SS_HlyB.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005074; Peptidase_C39.
DR InterPro; IPR039421; Type_1_exporter.
DR NCBIfam; TIGR01846; type_I_sec_HlyB; 1.
DR PANTHER; PTHR24221:SF658; ABC TRANSPORTER B FAMILY MEMBER 29, CHLOROPLASTIC; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF03412; Peptidase_C39; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS50990; PEPTIDASE_C39; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:SEP42762.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022807};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000256|ARBA:ARBA00022807};
KW Reference proteome {ECO:0000313|Proteomes:UP000198847};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 162..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 10..130
FT /note="Peptidase C39"
FT /evidence="ECO:0000259|PROSITE:PS50990"
FT DOMAIN 162..441
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 475..710
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 742 AA; 82577 MW; E5A6D6FCBD5C2443 CRC64;
MMTNGTLPPG ADKLDTALKC LLIVAGYYGI PAVDEQLRRA YVVKTGKMDT LTLVRAARGL
GFKARAFRDD AVRLNRMALP AIAVLKNGNY VVLGKWDGEA ALIIDPCREQ PFALPRENFL
QAWSGELVLF TRRIEATRKQ KKFGLSWFVP VIWRYRNLWG KVLGLSLLLQ LFGLASPFFT
QRIIDDVLVH HSVNSLDAML SGMIFVSLFQ TWITGVRTFL FTHATNQVDV MLGAKLFRQI
TALPVRYFET WQVGEVVARV RELENVRQFI TGSAITVVLD VVFTVVYMMV MFLYSTTLSI
IALLILPLYI LLNAVVTPLY RSRLQEQFAA GTENQTFLIE MVTGIHTVKA LAVEPQLLQE
WEQRLARYIE ASFRTANLAN IAGSTGTFIQ QFFILLVLWF GARQVMGDSL SVGGLMAFQM
LAGQIFAPVL RLVSLWQSFQ QVGVSVERLG DIMNETAEPA FNPNRTTLPA VRGDIVFDRV
TFRYRQDATE VLQQVKLQIR AESSVGIVGR SGSGKSTLTK LMQRLYVPES GRILIDGVDL
AQVEPAWLRR QIGVVLQDTF LFNGTVRDNI AAACPGASIA DVVKAARMSG AHEFISEMAQ
GYDTAVGERG SALSGGQRQR LAIARALLTN PRILIFDEAT SALDYESEHR IMENLSQMAA
GRTLIMIAHR LSTVRHCDQI IVLDRGRVME QGSHEELVQL QGIYYSLYQQ QNPDGTGPAC
ESVTEAAAAD CPLKTHPKSG NW
//
