ID   A0A1H8Y751_9PSEU        Unreviewed;       378 AA.
AC   A0A1H8Y751;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Signal transduction histidine kinase {ECO:0000313|EMBL:SEP47922.1};
GN   ORFNames=SAMN04489732_111249 {ECO:0000313|EMBL:SEP47922.1};
OS   Amycolatopsis saalfeldensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=394193 {ECO:0000313|EMBL:SEP47922.1, ECO:0000313|Proteomes:UP000198582};
RN   [1] {ECO:0000313|EMBL:SEP47922.1, ECO:0000313|Proteomes:UP000198582}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44993 {ECO:0000313|EMBL:SEP47922.1,
RC   ECO:0000313|Proteomes:UP000198582};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOEF01000011; SEP47922.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H8Y751; -.
DR   STRING; 394193.SAMN04489732_111249; -.
DR   OrthoDB; 5242012at2; -.
DR   Proteomes; UP000198582; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR   Gene3D; 1.20.5.1930; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR025828; Put_sensor_dom.
DR   InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR   PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR   PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR   Pfam; PF07730; HisKA_3; 1.
DR   Pfam; PF13796; Sensor; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SEP47922.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198582};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   TRANSMEM        20..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          22..127
FT                   /note="Putative sensor"
FT                   /evidence="ECO:0000259|Pfam:PF13796"
FT   DOMAIN          188..253
FT                   /note="Signal transduction histidine kinase subgroup 3
FT                   dimerisation and phosphoacceptor"
FT                   /evidence="ECO:0000259|Pfam:PF07730"
SQ   SEQUENCE   378 AA;  41086 MW;  0C7F2B7F458835B5 CRC64;
     MTTEQQLPPE HPRPNPARTI VYMIVSFVFR LVQFILIVVG AVVGVATVVV WVGFPILLAT
     TGFVRWSGDM ERRWARTMLR SPLTSVERLP LEGQSLTRRW LTRLTDPTTW RDLSYLMIAF
     PLAVAELPVA IASIVLLPMA IWVTPWLGWL HGNLAMSLLG PNRTKKLEAK AEHLQASRAR
     GVDAAEAERR RIERDLHDGA QQRLVAVAMS LGRAKSKFDN DPDAVRDLID EAHSDAKLAV
     SELRDLARGI FPAVLGDRGL DAALSAQAAK SPIPVDVHVN VEPRPPAAVE TTAYFIVGET
     LTNIAKHSGA TEAIVKVWRS DTHVIVEITD NGHGGAEVRP GGGLAGLADR AATIDGVITV
     VSPVGGPTVI RADLPCQW
//