ID A0A1H8YJ79_9PSEU Unreviewed; 340 AA.
AC A0A1H8YJ79;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=L-threonine aldolase {ECO:0000313|EMBL:SEP52230.1};
GN ORFNames=SAMN04489732_119112 {ECO:0000313|EMBL:SEP52230.1};
OS Amycolatopsis saalfeldensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=394193 {ECO:0000313|EMBL:SEP52230.1, ECO:0000313|Proteomes:UP000198582};
RN [1] {ECO:0000313|EMBL:SEP52230.1, ECO:0000313|Proteomes:UP000198582}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44993 {ECO:0000313|EMBL:SEP52230.1,
RC ECO:0000313|Proteomes:UP000198582};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the threonine aldolase family.
CC {ECO:0000256|ARBA:ARBA00006966}.
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DR EMBL; FOEF01000019; SEP52230.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H8YJ79; -.
DR STRING; 394193.SAMN04489732_119112; -.
DR OrthoDB; 9774495at2; -.
DR Proteomes; UP000198582; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR023603; Low_specificity_L-TA-like.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; NF041359; GntG_guanitoxin; 1.
DR PANTHER; PTHR48097:SF9; L-THREONINE ALDOLASE; 1.
DR PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR PIRSF; PIRSF017617; Thr_aldolase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000198582}.
FT DOMAIN 9..292
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
FT MOD_RES 208
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR017617-1"
SQ SEQUENCE 340 AA; 36065 MW; 004A80B65676449A CRC64;
MTWTPQPLDF RSDTVTRPDE VMRRAMAEAE VDDNVIGHDP TIAKLEERAA QTLGMPAALW
TPSGTMANLI ALSVHLERGD RFLATRGAHV LVNELGSAAW LAGGMPDILE HDAGPGRCTP
DALSAAISPD GPYYTLRTRL LCLENTHNAA GGAVTPPDEH AQLMSVAKQA GLTVHLDGAR
IWHAAVALEV PPAALTVGVD SVSACFSKGL GAPVGSVVAG SVEFVERAQR MRQMLGGGVR
QGGVLAAACL VALGRVDELA ESHELARRLA AGLSEHGWGV RTPDTNIVLA DVPDLRTAEE
WLDSLGIRTS RMAGKVRFVT HRDLAATDVE EALRRIKNGV
//
