ID   A0A1H9BHN0_9BACT        Unreviewed;       762 AA.
AC   A0A1H9BHN0;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Oxidoreductase alpha (Molybdopterin) subunit {ECO:0000313|EMBL:SEP87768.1};
GN   ORFNames=SAMN05444359_103110 {ECO:0000313|EMBL:SEP87768.1};
OS   Neolewinella agarilytica.
OC   Bacteria; Bacteroidota; Saprospiria; Saprospirales; Lewinellaceae;
OC   Neolewinella.
OX   NCBI_TaxID=478744 {ECO:0000313|EMBL:SEP87768.1, ECO:0000313|Proteomes:UP000199021};
RN   [1] {ECO:0000313|Proteomes:UP000199021}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 24740 {ECO:0000313|Proteomes:UP000199021};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mo-bis(molybdopterin guanine dinucleotide);
CC         Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
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DR   EMBL; FOFB01000003; SEP87768.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9BHN0; -.
DR   STRING; 478744.SAMN05444359_103110; -.
DR   InParanoid; A0A1H9BHN0; -.
DR   OrthoDB; 9792592at2; -.
DR   Proteomes; UP000199021; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   CDD; cd02787; MopB_CT_ydeP; 1.
DR   CDD; cd02767; MopB_ydeP; 1.
DR   Gene3D; 2.40.40.20; -; 1.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR037951; MopB_CT_YdeP.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR010046; Mopterin_OxRdtse_a_bac.
DR   InterPro; IPR041953; YdeP_MopB.
DR   NCBIfam; TIGR01701; Fdhalpha-like; 1.
DR   PANTHER; PTHR43105:SF4; PROTEIN YDEP; 1.
DR   PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   PIRSF; PIRSF000144; CbbBc; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199021}.
FT   DOMAIN          120..567
FT                   /note="Molybdopterin oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00384"
FT   DOMAIN          648..751
FT                   /note="Molybdopterin dinucleotide-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01568"
SQ   SEQUENCE   762 AA;  84149 MW;  9A1970587F25E3CA CRC64;
     MPNELTPERL KGLELREPYD YAAGISGVKV SLQHVNEYMN FGEGMHALLK LNQKDGFDCP
     GCAWPDPDGR RSPVAEYCEN GAKAIAEEAT KNRATPEWFA QHSIDELGDM TDFELGKSGR
     ITQPMYLAPG ATHYTPVSWD DAFGIIANEL NGLDSPDEAI FYTSGRASNE AAFLYQLFVR
     QFGTNNLPDC SNMCHESTGT ALSKVIGIGK GTTTLQDLHE ADLIIMLGQN PGTNHPRQLS
     ALKTCKDNGG RIISVNPLPE TGLMRFVDPQ DPINILKRGT KLTDLFLQVR INEDMSLVRA
     ICKILWEKEK EAPGTVFDQE FIEQHTAGYE AWTNMLEATD LEQCISGCGI DRDQIEEAAG
     LIHGSEKIVL CYAMGLTQHE NSVDVIKEMV NLLLLKGSIG KPGAGICPVR GHSNVQGDRT
     VGVWEKLKPE LRDALRAHFN FEPPEKDGYD VVNSIKAMGE GRAKVFFGLG GNFLSATPDT
     VYTAKGLRQC KLTVHISTKP NRSHVVHGEQ ALILPCLGRT ETDIRAQGEQ FVSCENSMGV
     VQMSKGVLKP AGENLRSEVA IICGLASKTL GARSQVQWKD MSNDYDNVRD AIAACVPGFE
     RYNERVREPA GFYLPNGPRN RRFGTEDGKA HFTVSPLSCH ILEPGEYLMM TVRSHDQYNT
     TIYGMHDRYR GIHNERRIVM MNKADMAEAG LSTGDKVNLS SEYDGETRHA RLFQVVPYSI
     PRGNIGTYFP EANTLVPITR TARGSNTPIS KSVRVRITAL TD
//