ID A0A1H9BJL6_9BACT Unreviewed; 946 AA.
AC A0A1H9BJL6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=SAMN05444359_103134 {ECO:0000313|EMBL:SEP88468.1};
OS Neolewinella agarilytica.
OC Bacteria; Bacteroidota; Saprospiria; Saprospirales; Lewinellaceae;
OC Neolewinella.
OX NCBI_TaxID=478744 {ECO:0000313|EMBL:SEP88468.1, ECO:0000313|Proteomes:UP000199021};
RN [1] {ECO:0000313|Proteomes:UP000199021}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24740 {ECO:0000313|Proteomes:UP000199021};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; FOFB01000003; SEP88468.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9BJL6; -.
DR STRING; 478744.SAMN05444359_103134; -.
DR InParanoid; A0A1H9BJL6; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000199021; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF4; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000199021};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 356..595
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 608..940
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 946 AA; 104611 MW; 4F4D828AFF7482C4 CRC64;
MSKNSDLSAA DLRTSIFIKG AAANNLKSVD LVIPKNQLVV VTGVSGSGKS SITMDTLFAE
GQRRYVESLS SYARQFLMRM KKPEVDYIRG ICPAIAIEQK TTTANARSTV GTLTEIYDFF
RLLYARAGRT FSPISGKEVK RHRVTDVVDH ILAMDEGSRV HLYAPLPREY DDRTLRRELE
LLVQKGYTRV MADDEVKQIE DILEENLPSL AKTLIELEDH EEMMVLIDRF IVKADDEENN
KRIADSVQTS FSEGGGEVIV YLDADNWTAW NNRFELDGMT FMEPSPSLFN YNNPAGACPT
CEGFGRTMGI DEDKVIPDPS KSVYDGAVAP WSGATFGSWQ KDFLRQANKF EFPVHTPYGD
LTKDQQRVLW EGNRHVGGIT DFFDQLGKKL YKIQNRIMLA RYRGRTTCHT CRGGRLRREA
EYVKVGGTAI TELIDLPIDQ LQTYFKNIKL NEHDATIARR LLLEINNRLK SMMDLGLSYL
TINRLSSTLS GGESQRINLT RTLGSNLTAS MYILDEPSVG LHPRDTERLV AVLRRLRDLG
NTVLVVEHEE GVIAAADYLI DVGPAAGIHG GEIVFAGPYE DIHSEAADSL TTKYMNGTMS
VPVPEQRRRL TNWLNIEGAR MHNLKKIDAK IPLNALTVIS GVSGSGKTSL IKGILYPALR
RELGEGSSQA PGPHAGLSGD LKILTQVEMV SQSPIGKSSR SNPVTYVGAY DTIRAMMADQ
QLSKIRGYGP GHFSFNVDGG RCPTCKGEGE QTVEMQFLAD VRLVCEECNG ARFKRELLDV
NYNGKNISEI LDLSVDEAVD FFAEEASISR KLKPLQDVGL GYITLGQASS TLSGGEAQRV
KLASFLTKEK KGEHIFFIFD EPTTGLHFHD VAILLTALNA LVERGHTVLV VEHNMDVIKS
ADYLIDLGPE GGRDGGHIVF QGTPEALVEN GEGFTAGYLK EALAGN
//
